4Z3M

X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Complex with S,O Bidentate Ligands (9b)

Summary for 4Z3M
DescriptorLysozyme C, 3-[2-chloranyl-2-[dimethyl(oxidanyl)-{4}-sulfanyl]-4-ethylsulfanyl-1-oxa-3{3}-thia-2{4}-platinacyclohexa-3,5-dien-6-yl]phenol, DIMETHYL SULFOXIDE, ... (6 entities in total)
Functional Keywordspt compounds, anticancer agents, lysozyme complexes, hydrolase
Biological sourceGallus gallus (Chicken)
Cellular locationSecreted: P00698
Total number of polymer chains1
Total formula weight15392.59
Authors
Merlino, A. (deposition date: 2015-03-31, release date: 2015-09-02, Last modification date: 2015-09-16)
Primary citationFerraro, G.,Hildebrandt, J.,Marzo, T.,Massai, L.,Merlino, A.,Messori, L.,Metzler-Nolte, N.,Mugge, C.,Rivera-Fuentes, P.,Weigand, W.
Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding.
Inorg.Chem., 54:8560-8570, 2015
PubMed: 26280387
DOI: 110.1021/acs.inorgchem.5b01238
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation
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PDB entries from 2021-06-16