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8D0W
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BU of 8d0w by Molmil
Human FUT9 bound to H-Type 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.332 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0O
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Human alpha1,3-fucosyltransferase FUT9, heavy atom derivative
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, CESIUM ION, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0R
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Human FUT9 bound to GDP and H-Type 2
分子名称: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0P
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Human FUT9, unliganded
分子名称: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, SULFATE ION, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0U
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BU of 8d0u by Molmil
Human FUT9 bound to GDP
分子名称: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0S
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BU of 8d0s by Molmil
Human FUT9 bound to GDP and LNnT
分子名称: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0X
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Human FUT9 bound to LNnT
分子名称: 1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
8D0Q
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BU of 8d0q by Molmil
Human FUT9 bound to GDP-CF3-Fucose and H-Type 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2022-05-26
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
1ZYN
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BU of 1zyn by Molmil
Oxidized structure of the N-terminal domain of Salmonella typhimurium AhpF
分子名称: Alkyl hydroperoxide reductase subunit F
著者Roberts, B.R, Wood, Z.A, Jonsson, T.J, Poole, L.B, Karplus, P.A.
登録日2005-06-10
公開日2005-06-21
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF
Protein Sci., 14, 2005
1ZYP
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BU of 1zyp by Molmil
Synchrotron reduced form of the N-terminal domain of Salmonella typhimurium AhpF
分子名称: Alkyl hydroperoxide reductase subunit F
著者Roberts, B.R, Wood, Z.A, Jonsson, T.J, Poole, L.B, Karplus, P.A.
登録日2005-06-10
公開日2005-06-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF
Protein Sci., 14, 2005
6WMO
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BU of 6wmo by Molmil
Human poly-N-acetyl-lactosamine synthase structure demonstrates a modular assembly of catalytic subsites for GT-A glycosyltransferases
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-04-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites.
J.Biol.Chem., 296, 2020
6WMN
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BU of 6wmn by Molmil
Human poly-N-acetyl-lactosamine synthase structure demonstrates a modular assembly of catalytic subsites for GT-A glycosyltransferases
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-04-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites.
J.Biol.Chem., 296, 2020
6X5H
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BU of 6x5h by Molmil
Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP
分子名称: 1,2-ETHANEDIOL, Alpha-(1,6)-fucosyltransferase, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
6WMM
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BU of 6wmm by Molmil
Human poly-N-acetyl-lactosamine synthase structure demonstrates a modular assembly of catalytic subsites for GT-A glycosyltransferases
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-04-21
公開日2020-12-02
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (1.548 Å)
主引用文献Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites.
J.Biol.Chem., 296, 2020
6X5R
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BU of 6x5r by Molmil
Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A2-Asn
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A2-Asn, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
6X5T
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BU of 6x5t by Molmil
Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A3-Asn
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-(1,6)-fucosyltransferase, GLYCEROL, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
6X5S
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BU of 6x5s by Molmil
Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A3'-Asn
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A3'-Asn, Alpha-(1,6)-fucosyltransferase, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
6X5U
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Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and NM5M2-Asn
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kadirvelraj, R, Wood, Z.A.
登録日2020-05-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
J.Biol.Chem., 295, 2020
4M55
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BU of 4m55 by Molmil
Crystal structure of Human UDP-xylose synthase R236H substitution
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYROPHOSPHATE 2-, SULFATE ION, ...
著者Walsh Jr, R.M, Polizzi, S.J, Wood, Z.A.
登録日2013-08-08
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation.
Biochemistry, 54, 2015
5TJH
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BU of 5tjh by Molmil
hUGDH A136M Substitution
分子名称: CHLORIDE ION, PYROPHOSPHATE 2-, UDP-glucose 6-dehydrogenase, ...
著者Beattie, N.R, Wood, Z.A.
登録日2016-10-04
公開日2016-11-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Allostery and Hysteresis Are Coupled in Human UDP-Glucose Dehydrogenase.
Biochemistry, 56, 2017
5VCM
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BU of 5vcm by Molmil
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound UDP and Manganese
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, ...
著者Sanders, J.H, Kadirvelraj, R, Wood, Z.A.
登録日2017-03-31
公開日2018-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VCR
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BU of 5vcr by Molmil
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound uranium dioxide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, CHLORIDE ION, ...
著者Sanders, J.H, Kadirvelraj, R, Wood, Z.A.
登録日2017-03-31
公開日2018-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4RJT
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BU of 4rjt by Molmil
Crystal Structure of Unliganded, Full Length hUGDH at pH 7.0
分子名称: CHLORIDE ION, UDP-glucose 6-dehydrogenase
著者Sidlo, A.M, Wood, Z.A.
登録日2014-10-09
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Hysteresis in Human UDP-Glucose Dehydrogenase Is Due to a Restrained Hexameric Structure That Favors Feedback Inhibition.
Biochemistry, 53, 2014
4LK3
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BU of 4lk3 by Molmil
Crystal structure of Human UDP-xylose synthase R236A substitution
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYROPHOSPHATE 2-, SULFATE ION, ...
著者Walsh Jr, R.M, Polizzi, S.J, Wood, Z.A.
登録日2013-07-05
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation.
Biochemistry, 54, 2015
6C4J
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Ligand bound full length hUGDH with A104L substitution
分子名称: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-1,2-PROPANEDIOL, ...
著者Beattie, N.R, Pioso, B.J, Wood, Z.A, Sidlo, A.M.
登録日2018-01-12
公開日2018-05-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core.
Biochemistry, 57, 2018

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