6X5S

Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A3'-Asn

Summary for 6X5S

• Entry DOI: 10.2210/pdb6x5s/pdb
• Related: 6X5H 6X5R 6X5T 6X5U
• Descriptor: Alpha-(1,6)-fucosyltransferase, A3'-Asn, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: glycosyl transferase, fucosyl transferase, gt-b fold, inverting, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 112704.70

Authors

Kadirvelraj, R.,Wood, Z.A. (deposition date: 2020-05-26, release date: 2020-10-07, Last modification date: 2023-10-18)

• Primary citation: Boruah, B.M.,Kadirvelraj, R.,Liu, L.,Ramiah, A.,Li, C.,Zong, G.,Bosman, G.P.,Yang, J.Y.,Wang, L.X.,Boons, G.J.,Wood, Z.A.,Moremen, K.W.; Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.; J.Biol.Chem., 295:17027-17045, 2020; PubMed: 33004438; DOI: 10.1074/jbc.RA120.014625

Experimental method

X-RAY DIFFRACTION (3.3 Å)