4RJT
Crystal Structure of Unliganded, Full Length hUGDH at pH 7.0
Summary for 4RJT
Entry DOI | 10.2210/pdb4rjt/pdb |
Related | 2Q3E 2QG4 3PRJ 3PTZ 3TF5 4QEJ |
Descriptor | UDP-glucose 6-dehydrogenase, CHLORIDE ION (3 entities in total) |
Functional Keywords | oxidoreductase, rossman fold, nucleotide sugar dehydrogenase, nad binding, udp-glucose binding, oxidation, cytosol |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 165423.63 |
Authors | Sidlo, A.M.,Wood, Z.A. (deposition date: 2014-10-09, release date: 2014-12-31, Last modification date: 2023-09-20) |
Primary citation | Kadirvelraj, R.,Custer, G.S.,Keul, N.D.,Sennett, N.C.,Sidlo, A.M.,Walsh Jr., R.M.,Wood, Z.A. Hysteresis in Human UDP-Glucose Dehydrogenase Is Due to a Restrained Hexameric Structure That Favors Feedback Inhibition. Biochemistry, 53:8043-8051, 2014 Cited by PubMed: 25478983DOI: 10.1021/bi500594x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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