3PRJ

Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase.

Summary for 3PRJ

• Entry DOI: 10.2210/pdb3prj/pdb
• Related: 3PTZ
• Descriptor: UDP-glucose 6-dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE, ... (4 entities in total)
• Functional Keywords: feedback inhibition, rossmann fold, nucleotide sugar dehydrogenase, nad binding, cytosol, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 337773.93

Authors

Kadirvelraj, R.,Wood, Z.A. (deposition date: 2010-11-29, release date: 2011-06-15, Last modification date: 2024-02-21)

• Primary citation: Kadirvelraj, R.,Sennett, N.C.,Polizzi, S.J.,Weitzel, S.,Wood, Z.A.; Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase.; Biochemistry, 50:5780-5789, 2011; PubMed: 21595445; DOI: 10.1021/bi2005637

Experimental method

X-RAY DIFFRACTION (3.1 Å)