6X5H

Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP

Summary for 6X5H

Entry DOI	10.2210/pdb6x5h/pdb
Descriptor	Alpha-(1,6)-fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	glycosyl transferase, fucosyl transferase, gt-b fold, inverting, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	249699.53
Authors	Kadirvelraj, R.,Wood, Z.A. (deposition date: 2020-05-26, release date: 2020-10-07, Last modification date: 2023-10-18)
Primary citation	Boruah, B.M.,Kadirvelraj, R.,Liu, L.,Ramiah, A.,Li, C.,Zong, G.,Bosman, G.P.,Yang, J.Y.,Wang, L.X.,Boons, G.J.,Wood, Z.A.,Moremen, K.W. Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases. J.Biol.Chem., 295:17027-17045, 2020 Cited by PubMed: 33004438 DOI: 10.1074/jbc.RA120.014625 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation