6WMM

Human poly-N-acetyl-lactosamine synthase structure demonstrates a modular assembly of catalytic subsites for GT-A glycosyltransferases

Summary for 6WMM

Entry DOI	10.2210/pdb6wmm/pdb
Descriptor	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (8 entities in total)
Functional Keywords	glycosyltransferase, gt-a fold, poly lacnac synthesis, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	88262.53
Authors	Kadirvelraj, R.,Wood, Z.A. (deposition date: 2020-04-21, release date: 2020-12-02, Last modification date: 2021-04-28)
Primary citation	Kadirvelraj, R.,Yang, J.Y.,Kim, H.W.,Sanders, J.H.,Moremen, K.W.,Wood, Z.A. Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites. J.Biol.Chem., 296:100110-100110, 2020 Cited by PubMed: 33229435 DOI: 10.1074/jbc.RA120.015305 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.548 Å)

Structure validation