8D0O
Human alpha1,3-fucosyltransferase FUT9, heavy atom derivative
Summary for 8D0O
Entry DOI | 10.2210/pdb8d0o/pdb |
Descriptor | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IODIDE ION, ... (5 entities in total) |
Functional Keywords | glycosyltransferase, alpha-(1, 3)-fucosyltransferase, gt 10, gt-b fold, inverting mechanism, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 41249.83 |
Authors | Kadirvelraj, R.,Wood, Z.A. (deposition date: 2022-05-26, release date: 2023-05-24, Last modification date: 2023-08-09) |
Primary citation | Kadirvelraj, R.,Boruah, B.M.,Wang, S.,Chapla, D.,Huang, C.,Ramiah, A.,Hudson, K.L.,Prudden, A.R.,Boons, G.J.,Withers, S.G.,Wood, Z.A.,Moremen, K.W. Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19:1022-1030, 2023 Cited by PubMed: 37202521DOI: 10.1038/s41589-023-01345-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report