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4F3F
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Crystal Structure of Msln7-64 MORAb-009 FAB complex
分子名称: MORAb-009 Fab heavy chain, MORAb-009 Fab light chain, Mesothelin
著者Xia, D, Pastan, I, Ma, J, Tang, W.K, Esser, L.
登録日2012-05-09
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
7U9J
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BU of 7u9j by Molmil
Crystal structure of Mesothelin-207 fragment
分子名称: GLYCEROL, Isoform 3 of Mesothelin, SULFATE ION
著者Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D.
登録日2022-03-10
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
7UED
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BU of 7ued by Molmil
Crystal structure of full length mesothelin bound with MORAb-009 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Isoform 4 of Mesothelin, ...
著者Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D.
登録日2022-03-21
公開日2023-02-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
5C6R
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BU of 5c6r by Molmil
Crystal structure of PH domain of ASAP1
分子名称: Arf-GAP, PHOSPHATE ION, TRIETHYLENE GLYCOL
著者Xia, D, Tang, W.K.
登録日2015-06-23
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Structure, 23, 2015
8DFH
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BU of 8dfh by Molmil
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
分子名称: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
分子名称: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
分子名称: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
著者Patel, P.N, Tang, W.K, Tolia, N.H.
登録日2022-06-22
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
5KLI
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BU of 5kli by Molmil
Rhodobacter sphaeroides bc1 with stigmatellin and antimycin
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (2R,3S,6S,7R,8R)-3-{[3-(FORMYLAMINO)-2-HYDROXYBENZOYL]AMINO}-8-HEXYL-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL (2S)-2-METHYLBUTANOATE, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-24
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
5KLV
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BU of 5klv by Molmil
Structure of bos taurus cytochrome bc1 with fenamidone inhibited
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ...
著者Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z.
登録日2016-06-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
8E1Z
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BU of 8e1z by Molmil
Crystal structure of Plasmodium falciparum ookinete surface antigen Pfs28
分子名称: CHLORIDE ION, Ookinete surface protein Pfs28, SULFATE ION
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-08-12
公開日2022-11-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design.
Sci Rep, 12, 2022
5KKZ
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BU of 5kkz by Molmil
Rhodobacter sphaeroides bc1 with famoxadone
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, ASCORBIC ACID, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-23
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
8EZL
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BU of 8ezl by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-50
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZM
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BU of 8ezm by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-63
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ...
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZK
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BU of 8ezk by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-04
分子名称: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-4, single-chain Fv
著者Shukla, N, Tang, W.K, Tolia, N.H.
登録日2022-11-01
公開日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
5C79
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BU of 5c79 by Molmil
PH domain of ASAP1 in complex with diC4-PtdIns(4,5)P2
分子名称: (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, Arf-GAP, CHLORIDE ION
著者Xia, D, Tang, W.K.
登録日2015-06-24
公開日2015-10-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Structure, 23, 2015
6UKO
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BU of 6uko by Molmil
Structure analysis of full-length mouse bcs1 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Xia, D, Esser, L.
登録日2019-10-05
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
3HU1
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BU of 3hu1 by Molmil
Structure of p97 N-D1 R95G mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
3HU3
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BU of 3hu3 by Molmil
Structure of p97 N-D1 R155H mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
3HU2
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BU of 3hu2 by Molmil
Structure of p97 N-D1 R86A mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
7K3Z
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BU of 7k3z by Molmil
P. falciparum Cpn60 D474A mutant bound to ATP
分子名称: 60 kDa chaperonin, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Tolia, N.H, Shi, D, Nguyen, B.
登録日2020-09-14
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding.
Sci Rep, 11, 2021
4F8N
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BU of 4f8n by Molmil
X-ray structure of PsaA from Yersinia pestis, in complex with galactose and phosphate choline
分子名称: CHLORIDE ION, GUANIDINE, PHOSPHOCHOLINE, ...
著者Bao, R, Esser, L, Xia, D.
登録日2012-05-17
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F8P
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BU of 4f8p by Molmil
X-ray structure of PsaA from Yersinia pestis, in complex with galactose
分子名称: ACETATE ION, TERT-BUTYL FORMATE, beta-D-galactopyranose, ...
著者Bao, R, Esser, L, Xia, D.
登録日2012-05-17
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F8O
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BU of 4f8o by Molmil
X-ray structure of PsaA from Yersinia pestis, in complex with lactose and AEBSF
分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CHLORIDE ION, GUANIDINE, ...
著者Bao, R, Esser, L, Xia, D.
登録日2012-05-17
公開日2013-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F8L
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BU of 4f8l by Molmil
X-ray structure of PsaA from Yersinia pestis, in complex with galactose and AEBSF
分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, BROMIDE ION, GLYCINE, ...
著者Bao, R, Esser, L, Xia, D.
登録日2012-05-17
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis.
Proc.Natl.Acad.Sci.USA, 110, 2013
8DCC
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BU of 8dcc by Molmil
SARS-CoV-2 Receptor-Binding Domain SPEEDesign Immunogen 3 Bound to P2B-2F6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2B-2F6 Fab heavy chain, P2B-2F6 Fab light chain, ...
著者Dickey, T.D, Tolia, N.H.
登録日2022-06-16
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response.
Sci Adv, 8, 2022

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