2AG4
 
 | | Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine | | 分子名称: | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, Ganglioside GM2 activator, ISOPROPYL ALCOHOL, ... | | 著者 | Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F. | | 登録日 | 2005-07-26 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
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5K38
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5K74
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5K3L
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5K3N
 | | Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209 | | 分子名称: | (3S)-3-(2H-1,3-benzodioxol-5-yl)-1-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one, Nuclear receptor ROR-gamma | | 著者 | Huang, P, Rastinejad, F, Lu, J. | | 登録日 | 2016-05-19 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.666 Å) | | 主引用文献 | Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209
To be published
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5K3M
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4ZQD
 | | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with the Benzoxadiazole Antagonist 0X3 | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | | 著者 | Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F. | | 登録日 | 2015-05-09 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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5K6E
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4ZPR
 | | Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | | 著者 | Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F. | | 登録日 | 2015-05-08 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.902 Å) | | 主引用文献 | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZPK
 | | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | | 著者 | Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F. | | 登録日 | 2015-05-08 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZP4
 | | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | | 著者 | Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F. | | 登録日 | 2015-05-07 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.355 Å) | | 主引用文献 | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZPH
 | | Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with Proflavine | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN | | 著者 | Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F. | | 登録日 | 2015-05-07 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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1A6Y
 | | REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX | | 分子名称: | DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), ORPHAN NUCLEAR RECEPTOR NR1D1, ... | | 著者 | Zhao, Q, Khorasanizadeh, S, Rastinejad, F. | | 登録日 | 1998-03-04 | | 公開日 | 1998-10-21 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural elements of an orphan nuclear receptor-DNA complex.
Mol.Cell, 1, 1998
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1BY4
 | | STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA | | 分子名称: | DNA (5'-D(*C*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*A)-3'), PROTEIN (RETINOIC ACID RECEPTOR RXR-ALPHA), ... | | 著者 | Zhao, Q, Chasse, S.A, Devarakonda, S, Sierk, M.L, Ahvazi, B, Sigler, P.B, Rastinejad, F. | | 登録日 | 1998-10-22 | | 公開日 | 2000-01-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of RXR-DNA interactions.
J.Mol.Biol., 296, 2000
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1A62
 | | CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE TRANSCRIPTIONAL TERMINATOR PROTEIN RHO | | 分子名称: | RHO | | 著者 | Allison, T.J, Wood, T.C, Briercheck, D.M, Rastinejad, F, Richardson, J.P, Rule, G.S. | | 登録日 | 1998-03-05 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of the RNA-binding domain from transcription termination factor rho.
Nat.Struct.Biol., 5, 1998
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1PU5
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1OT7
 | | Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR | | 分子名称: | 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile Acid Receptor, ISO-URSODEOXYCHOLIC ACID, ... | | 著者 | Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F. | | 登録日 | 2003-03-21 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
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1OSV
 | | STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR | | 分子名称: | 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile acid receptor, Nuclear receptor coactivator 2 | | 著者 | Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F. | | 登録日 | 2003-03-20 | | 公開日 | 2004-03-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
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1P9P
 | | The Crystal Structure of a M1G37 tRNA Methyltransferase, TrmD | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Guanine-N(1)-)-methyltransferase | | 著者 | Elkins, P.A, Watts, J.M, Zalacain, M, Van Thiel, A, Vitaszka, P.R, Redlak, M, Andraos-Selim, C, Rastinejad, F, Holmes, W.M. | | 登録日 | 2003-05-12 | | 公開日 | 2004-05-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
J.Mol.Biol., 333, 2003
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1R0O
 | | Crystal Structure of the Heterodimeric Ecdysone Receptor DNA-binding Complex | | 分子名称: | Ecdysone Response Element, Ecdysone receptor, Ultraspiracle protein, ... | | 著者 | Devarakonda, S, Harp, J.M, Kim, Y, Ozyhar, A, Rastinejad, F. | | 登録日 | 2003-09-22 | | 公開日 | 2003-10-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structure of the Heterodimeric Ecdysone Receptor DNA-binding Complex
Embo J., 22, 2003
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1R0N
 | | Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex | | 分子名称: | Ecdsyone Response Element, Ecdysone Response Element, Ecdysone receptor, ... | | 著者 | Devarakonda, S, Harp, J.M, Kim, Y, Ozyhar, A, Rastinejad, F. | | 登録日 | 2003-09-22 | | 公開日 | 2003-10-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the heterodimeric Ecdysone Receptor DNA-binding complex
Embo J., 22, 2003
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1PUB
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5SY5
 | | Crystal Structure of the Heterodimeric NPAS1-ARNT Complex | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1 | | 著者 | Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. | | 登録日 | 2016-08-10 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | | 主引用文献 | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
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5SY7
 | | Crystal Structure of the Heterodimeric NPAS3-ARNT Complex with HRE DNA | | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | | 著者 | Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F. | | 登録日 | 2016-08-10 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
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2B2T
 | | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3 | | 分子名称: | Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail | | 著者 | Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S. | | 登録日 | 2005-09-19 | | 公開日 | 2005-12-27 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
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