5K74

Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with SBI0655870

Summary for 5K74

Entry DOI	10.2210/pdb5k74/pdb
Descriptor	Nuclear receptor ROR-gamma, ~{N}-[[3-methyl-4-(4-methylsulfonylphenyl)phenyl]methyl]-~{N}-(2-methylpropyl)-1-phenyl-methanesulfonamide (3 entities in total)
Functional Keywords	double helix, transcription
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : P51449
Total number of polymer chains	2
Total formula weight	58413.90
Authors	Lu, J.,Rastinejad, F. (deposition date: 2016-05-25, release date: 2017-05-31, Last modification date: 2024-05-22)
Primary citation	Lu, J.,Rastinejad, F. Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with SBI0655870 To be published,
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation