5K3L

Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with 444

Summary for 5K3L

Entry DOI	10.2210/pdb5k3l/pdb
Related	5K38 5K3M 5K3N
Descriptor	Nuclear receptor ROR-gamma, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE (3 entities in total)
Functional Keywords	double helix, protein binding
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : P51449
Total number of polymer chains	4
Total formula weight	116810.49
Authors	Huang, P.,Rastinejad, F. (deposition date: 2016-05-19, release date: 2017-05-31, Last modification date: 2024-03-06)
Primary citation	Lu, J.,Rastinejad, F. Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with 444 To be published,
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation