6LDX
 
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6LDY
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4TSN
 | | Crystal structure of FraC with POC bound (crystal form II) | | 分子名称: | ACETATE ION, Fragaceatoxin C, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | 登録日 | 2014-06-19 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
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6LDW
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4TSQ
 | | Crystal structure of FraC with DHPC bound (crystal form III) | | 分子名称: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, Fragaceatoxin C, ... | | 著者 | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | 登録日 | 2014-06-19 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
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6LDV
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6JB2
 | | Crystal structure of nanobody D3-L11 mutant Y102A in complex with hen egg-white lysozyme | | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | | 著者 | Caaveiro, J.M.M, Tamura, H, Akiba, H, Tsumoto, K. | | 登録日 | 2019-01-25 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody.
Sci Rep, 9, 2019
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6JB9
 | | Crystal structure of nanobody D3-L11 (unbound form) | | 分子名称: | Nanobody D3-L11, SULFATE ION | | 著者 | Caaveiro, J.M.M, Tamura, H, Akiba, H, Tsumoto, K. | | 登録日 | 2019-01-25 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody.
Sci Rep, 9, 2019
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6JB8
 | | Crystal structure of nanobody D3-L11 in complex with hen egg-white lysozyme | | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | | 著者 | Caaveiro, J.M.M, Tamura, H, Akiba, H, Tsumoto, K. | | 登録日 | 2019-01-25 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody.
Sci Rep, 9, 2019
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6JB5
 | | Crystal structure of nanobody D3-L11 mutant Y102A in complex with hen egg-white lysozyme (form II) | | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | | 著者 | Caaveiro, J.M.M, Tamura, H, Akiba, H, Tsumoto, K. | | 登録日 | 2019-01-25 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody.
Sci Rep, 9, 2019
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6K2G
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7CYM
 | | Crystal structure of LI-Cadherin EC1-4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Caaveiro, J.M.M, Yui, A, Tsumoto, K. | | 登録日 | 2020-09-03 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021
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7EV1
 | | Crystal structure of LI-Cadherin EC1-2 | | 分子名称: | ACETATE ION, CALCIUM ION, Cadherin-17, ... | | 著者 | Caaveiro, J.M.M, Yui, A, Tsumoto, K. | | 登録日 | 2021-05-19 | | 公開日 | 2021-06-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021
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7EKB
 | | Crystal structure of 4E10 modified with pyrene acetamide | | 分子名称: | ACETATE ION, Fab region of the heavy chain of broadly neutralizing antibody anti-HIV-1 4E10, Fab region of the light chain of the broadly neutralizing anti-HIV-1 antibody 4E10, ... | | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile.
Iscience, 24, 2021
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7EKK
 | | Anti-HIV-1 broadly neutralizing antibody delta-loop 4E10 modified with pyrene acetamide | | 分子名称: | AMMONIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile.
Iscience, 24, 2021
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4TSO
 | | Crystal structure of FraC with DHPC bound (crystal form I) | | 分子名称: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ... | | 著者 | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | 登録日 | 2014-06-19 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
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4TSP
 | | Crystal structure of FraC with DHPC bound (crystal form II) | | 分子名称: | 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Fragaceatoxin C, PHOSPHATE ION, ... | | 著者 | Caaveiro, J.M.M, Tanaka, K, Tsumoto, K. | | 登録日 | 2014-06-19 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
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7W81
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7XLI
 | | Crystal structure of IsdB linker-NEAT2 bound to a nanobody (VHH) | | 分子名称: | CALCIUM ION, CHLORIDE ION, Iron-regulated surface determinant protein B, ... | | 著者 | Caaveiro, J.M.M, Valenciano-Bellido, S, Tsumoto, K. | | 登録日 | 2022-04-21 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth.
J.Biol.Chem., 299, 2023
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7XLD
 | | Crystal structure of IsdH linker-NEAT3 bound to a nanobody (VHH) | | 分子名称: | Iron-regulated surface determinant protein H, MAGNESIUM ION, Nanobody VHH6, ... | | 著者 | Caaveiro, J.M.M, Valenciano-Bellido, S, Tsumoto, K. | | 登録日 | 2022-04-21 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth.
J.Biol.Chem., 299, 2023
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7WKI
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7XL0
 | | Crystal structure of Vobarilizumab at 1.70 Angstrom | | 分子名称: | GLYCEROL, Nanobody Vobarilizumab, SULFATE ION | | 著者 | Caaveiro, J.M.M, Mori, C, Kinoshita, S, Nakakido, M, Tsumoto, K. | | 登録日 | 2022-04-20 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3.
Protein Sci., 31, 2022
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7XAR
 | | Crystal structure of 3C-like protease from SARS-CoV-2 in complex with covalent inhibitor | | 分子名称: | 3C-like proteinase, 4-fluoranyl-~{N}-[(2~{S})-1-[2-(2-fluoranylethanoyl)-2-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]hydrazinyl]-4-methyl-1-oxidanylidene-pentan-2-yl]-1~{H}-indole-2-carboxamide, CHLORIDE ION, ... | | 著者 | Caaveiro, J.M.M, Ochi, J, Takahashi, D, Ueda, T, Ojida, A. | | 登録日 | 2022-03-18 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease.
J.Med.Chem., 65, 2022
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7XL1
 | | Crystal structure of chimeric 7D12-Vob nanobody at 1.65 Angstrom | | 分子名称: | Chimeric 7D12-Vob nanobody, MALONATE ION | | 著者 | Caaveiro, J.M.M, Kinoshita, S, Mori, C, Nakakido, M, Tsumoto, K. | | 登録日 | 2022-04-20 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3.
Protein Sci., 31, 2022
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3VGN
 | | Crystal Structure of Ketosteroid Isomerase D40N from Pseudomonas putida (pKSI) with bound 3-fluoro-4-nitrophenol | | 分子名称: | 3-fluoro-4-nitrophenol, Steroid Delta-isomerase | | 著者 | Caaveiro, J.M.M, Pybus, B, Ringe, D, Petsko, G.A, Sigala, P.A. | | 登録日 | 2011-08-16 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site
Proc.Natl.Acad.Sci.USA, 110, 2013
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