5CIL
Crystal Structure of non-neutralizing version of 4E10 (WDWD) with epitope bound
Summary for 5CIL
Entry DOI | 10.2210/pdb5cil/pdb |
Related | 5CIN 5CIP |
Descriptor | FAB 4E10 HEAVY CHAIN, FAB 4E10 LIGHT CHAIN, Peptide from the MPER region of the ENV protein of HIV-1, ... (7 entities in total) |
Functional Keywords | broadly neutralizing antibody, recombinant fab, env-peptide, hiv-1, epitope, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 49198.73 |
Authors | Caaveiro, J.M.M.,Rujas, E.,Nieva, J.L.,Tsumoto, K. (deposition date: 2015-07-13, release date: 2015-09-23, Last modification date: 2023-11-08) |
Primary citation | Rujas, E.,Gulzar, N.,Morante, K.,Tsumoto, K.,Scott, J.K.,Nieva, J.L.,Caaveiro, J.M.M. Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10 J.Virol., 89:11975-11989, 2015 Cited by PubMed: 26378169DOI: 10.1128/JVI.01793-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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