5CIN

Crystal Structure of non-neutralizing version of 4E10 (DeltaLoop) with epitope bound

Summary for 5CIN

Entry DOI	10.2210/pdb5cin/pdb
Related	5CIL 5CIP
Descriptor	FAB 4E10 HEAVY CHAIN, FAB 4E10 LIGHT CHAIN, Peptide from MPER region of HIV-1 ENV, ... (6 entities in total)
Functional Keywords	broadly neutralizing antibody, recombinant fab, env-peptide, hiv-1, epitope, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	49032.17
Authors	Caaveiro, J.M.M.,Rujas, E.,Nieva, J.L.,Tsumoto, K. (deposition date: 2015-07-13, release date: 2015-09-23, Last modification date: 2023-11-08)
Primary citation	Rujas, E.,Gulzar, N.,Morante, K.,Tsumoto, K.,Scott, J.K.,Nieva, J.L.,Caaveiro, J.M.M. Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10 J.Virol., 89:11975-11989, 2015 Cited by PubMed: 26378169 DOI: 10.1128/JVI.01793-15 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation