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7XLI

Crystal structure of IsdB linker-NEAT2 bound to a nanobody (VHH)

Summary for 7XLI
Entry DOI10.2210/pdb7xli/pdb
DescriptorIron-regulated surface determinant protein B, VHH6 nanobody, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsisdh system heme staphylococcus aureus vhh nanodoby antimicrobial, metal transport
Biological sourceStaphylococcus aureus subsp. aureus Mu50
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Total number of polymer chains2
Total formula weight36220.37
Authors
Caaveiro, J.M.M.,Valenciano-Bellido, S.,Tsumoto, K. (deposition date: 2022-04-21, release date: 2023-05-31, Last modification date: 2024-03-06)
Primary citationValenciano-Bellido, S.,Caaveiro, J.M.M.,Nakakido, M.,Kuroda, D.,Aikawa, C.,Nakagawa, I.,Tsumoto, K.
Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth.
J.Biol.Chem., 299:104927-104927, 2023
Cited by
PubMed: 37330175
DOI: 10.1016/j.jbc.2023.104927
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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