4TSY

Crystal structure of FraC with lipids

Summary for 4TSY

Entry DOI	10.2210/pdb4tsy/pdb
Related	3VWI 3WP9 4TSL 4TSN 4TSO 4TSP 4TSQ
Descriptor	Fragaceatoxin C, 2-[[(E,2S,3R)-2-(hexanoylamino)-3-oxidanyl-dec-4-enoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, SULFATE ION, ... (5 entities in total)
Functional Keywords	toxin, actinoporin pore-forming toxin, membrane lipids, phosphocholine, lipid-protein interaction
Biological source	Actinia fragacea (Strawberry anemone)
Total number of polymer chains	4
Total formula weight	86377.30
Authors	Caaveiro, J.M.M.,Tanaka, K.,Tsumoto, K. (deposition date: 2014-06-19, release date: 2015-03-04, Last modification date: 2023-11-08)
Primary citation	Tanaka, K.,Caaveiro, J.M.M.,Morante, K.,Gonzalez-Manas, J.M.,Tsumoto, K. Structural basis for self-assembly of a cytolytic pore lined by protein and lipid Nat Commun, 6:6337-6337, 2015 Cited by PubMed: 25716479 DOI: 10.1038/ncomms7337 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.14 Å)

Structure validation