7XL1
Crystal structure of chimeric 7D12-Vob nanobody at 1.65 Angstrom
Summary for 7XL1
| Entry DOI | 10.2210/pdb7xl1/pdb |
| Descriptor | Chimeric 7D12-Vob nanobody, MALONATE ION (3 entities in total) |
| Functional Keywords | nanobody vhh protein engineering protein stability surface plasmon resonance differential scanning calorimetry, immune system |
| Biological source | Lama glama |
| Total number of polymer chains | 2 |
| Total formula weight | 29174.02 |
| Authors | Caaveiro, J.M.M.,Kinoshita, S.,Mori, C.,Nakakido, M.,Tsumoto, K. (deposition date: 2022-04-20, release date: 2022-11-09, Last modification date: 2023-11-29) |
| Primary citation | Kinoshita, S.,Nakakido, M.,Mori, C.,Kuroda, D.,Caaveiro, J.M.M.,Tsumoto, K. Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3. Protein Sci., 31:e4450-e4450, 2022 Cited by PubMed: 36153698DOI: 10.1002/pro.4450 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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