7W81

Crystal structure of the heme-bound form of the linker-NEAT3 region of IsdH from Staphylococcus aureus

Summary for 7W81

Entry DOI	10.2210/pdb7w81/pdb
Descriptor	Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	iron acquisition, antimicrobial, hemoglobin, isd system, staphylococcus aureus, heme, metal transport
Biological source	Staphylococcus aureus (strain Mu50 / ATCC 700699)
Total number of polymer chains	2
Total formula weight	43302.54
Authors	Caaveiro, J.M.M.,Vu, N.,Tsumoto, K. (deposition date: 2021-12-07, release date: 2022-10-19, Last modification date: 2023-11-29)
Primary citation	Valenciano-Bellido, S.,Caaveiro, J.M.M.,Morante, K.,Sushko, T.,Nakakido, M.,Nagatoishi, S.,Tsumoto, K. Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus. J.Biol.Chem., 298:101995-101995, 2022 Cited by PubMed: 35500652 DOI: 10.1016/j.jbc.2022.101995 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation