8H62

Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12

Summary for 8H62

Entry DOI	10.2210/pdb8h62/pdb
Descriptor	Internalin A, Cadherin-1, CALCIUM ION, ... (5 entities in total)
Functional Keywords	internalin a cadherin bacterial invasion nanobody surface plasmon resonance isothermal titration calorimetry, cell invasion
Biological source	Listeria monocytogenes serovar 1/2a More
Total number of polymer chains	2
Total formula weight	73268.77
Authors	Caaveiro, J.M.M.,Nagatoish, S.,Tsumoto, K. (deposition date: 2022-10-14, release date: 2023-10-04, Last modification date: 2023-10-25)
Primary citation	Yamazaki, T.,Nagatoishi, S.,Yamawaki, T.,Nozawa, T.,Matsunaga, R.,Nakakido, M.,Caaveiro, J.M.M.,Nakagawa, I.,Tsumoto, K. Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes. J.Biol.Chem., 299:105254-105254, 2023 Cited by PubMed: 37716701 DOI: 10.1016/j.jbc.2023.105254 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation