8H62

Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005509	molecular_function	calcium ion binding
B	0005886	cellular_component	plasma membrane
B	0007155	biological_process	cell adhesion
B	0007156	biological_process	homophilic cell adhesion via plasma membrane adhesion molecules
B	0016020	cellular_component	membrane
B	0098609	biological_process	cell-cell adhesion

Functional Information from PROSITE/UniProt

site_id	PS00232
Number of Residues	11
Details	CADHERIN_1 Cadherin domain signature. ItVtDqNDNkP

Chain	Residue	Details
B	ILE96-PRO106

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
B	ASP103
B	ASP134

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Cleavage; by S.pyogenes SpeB => ECO:0000269|PubMed:23532847

Chain	Residue	Details
B	THR210

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: O-linked (Man...) serine => ECO:0000250|UniProtKB:P09803

Chain	Residue	Details
B	SER126

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: O-linked (Man...) threonine => ECO:0000250|UniProtKB:P09803

Chain	Residue	Details
B	THR131
B	THR204

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