5X08
Crystal structure of broadly neutralizing anti-HIV-1 antibody 4E10, mutant Npro, with peptide bound
Summary for 5X08
| Entry DOI | 10.2210/pdb5x08/pdb |
| Descriptor | Fab 4E10 Heavy chain, Fab 4E10 Light chain, Envelope glycoprotein gp160, ... (9 entities in total) |
| Functional Keywords | broadly neutralizing antibody, mper, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 3 |
| Total formula weight | 50375.73 |
| Authors | Caaveiro, J.M.M.,Rujas, E.,Nieva, J.L.,Tsumoto, K. (deposition date: 2017-01-20, release date: 2017-04-05, Last modification date: 2023-11-22) |
| Primary citation | Rujas, E.,Insausti, S.,Garcia-Porras, M.,Sanchez-Eugenia, R.,Tsumoto, K.,Nieva, J.L.,Caaveiro, J.M.M. Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane J. Mol. Biol., 429:1213-1226, 2017 Cited by PubMed: 28300601DOI: 10.1016/j.jmb.2017.03.008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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