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5X08

Crystal structure of broadly neutralizing anti-HIV-1 antibody 4E10, mutant Npro, with peptide bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Fab 4E10 Heavy chainpolymer23024184.31Homo sapiens
2B
(L)
Fab 4E10 Light chainpolymer21423292.71Homo sapiens
3C
(P)
Envelope glycoprotein gp160polymer162187.61UniProt (by SIFTS) (P04578)Human immunodeficiency virus type 1 (MAL ISOLATE)
4D, F
(H, L)
GLYCEROLnon-polymer92.12Chemie (GOL)
5E
(H)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
6G
(L)
HEXAETHYLENE GLYCOLnon-polymer282.31Chemie (P6G)
7H
(L)
CHLORIDE IONnon-polymer35.51Chemie (CL)
8I
(P)
ACETATE IONnon-polymer59.01Chemie (ACT)
9J, K, L
(H, L, P)
waterwater18.0481Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight49664.5
Non-Polymers*Number of molecules6
Total formula weight711.2
All*Total formula weight50375.7
*Water molecules are not included.

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PDB entries from 2025-12-17

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