4LB9
 
 | | X-ray study of human serum albumin complexed with etoposide | | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, MYRISTIC ACID, SERUM ALBUMIN | | 著者 | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | | 登録日 | 2013-06-20 | | 公開日 | 2013-07-24 | | 最終更新日 | 2014-02-19 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
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4L9K
 | | X-ray study of human serum albumin complexed with camptothecin | | 分子名称: | (2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]butanoic acid, SERUM ALBUMIN | | 著者 | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | | 登録日 | 2013-06-18 | | 公開日 | 2013-07-24 | | 最終更新日 | 2013-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
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4L8U
 | | X-ray study of human serum albumin complexed with 9 amino camptothecin | | 分子名称: | (2S)-2-[1-amino-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid, MYRISTIC ACID, Serum albumin | | 著者 | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | | 登録日 | 2013-06-17 | | 公開日 | 2013-07-24 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
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4LA0
 | | X-ray study of human serum albumin complexed with bicalutamide | | 分子名称: | R-BICALUTAMIDE, SERUM ALBUMIN | | 著者 | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | | 登録日 | 2013-06-18 | | 公開日 | 2013-07-24 | | 最終更新日 | 2014-02-19 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
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4L9Q
 | | X-ray study of human serum albumin complexed with teniposide | | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside, SERUM ALBUMIN | | 著者 | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | | 登録日 | 2013-06-18 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
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7D3D
 | | Crystal structure of SPOP bound with a peptide | | 分子名称: | GLU-VAL-SER-ILE-ILE-GLN-GLY-ALA-ASP-SER-THR-THR, GLYCEROL, Speckle-type POZ protein | | 著者 | Yang, C.-G, Gan, J.H. | | 登録日 | 2020-09-18 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A peptide binder of E3 ligase adaptor SPOP disrupts oncogenic SPOP-protein interactions in kidney cancer cells.
Chin.J.Chem., 39, 2021
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7SYY
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7SYZ
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7UAP
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7UAQ
 | | Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1520 Fab Heavy Chain, ... | | 著者 | Barnes, C.O. | | 登録日 | 2022-03-13 | | 公開日 | 2022-04-27 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.
Immunity, 55, 2022
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7UAR
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8K3S
 | | Structure of PKD2-F604P complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | | 著者 | Chen, M.Y, Su, Q, Wang, Z.F, Yu, Y. | | 登録日 | 2023-07-16 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands.
Proc.Natl.Acad.Sci.USA, 121, 2024
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7CUT
 | | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with Z-VAD-FMK | | 分子名称: | 3C protein, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Lu, M, Yang, H.T, Wang, Z.Y, Zhao, Y, Xing, Y.F. | | 登録日 | 2020-08-24 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 M pro .
Signal Transduct Target Ther, 6, 2021
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7CUU
 | | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with MG132 | | 分子名称: | 3C protein, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Lu, M, Yang, H.T, Wang, Z.Y, Zhao, Y, Xing, Y.F. | | 登録日 | 2020-08-24 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 M pro .
Signal Transduct Target Ther, 6, 2021
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6J1X
 | | WWP1 close conformation | | 分子名称: | GLYCEROL, NEDD4-like E3 ubiquitin-protein ligase WWP1 | | 著者 | Liu, Z.H. | | 登録日 | 2018-12-30 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Nat Commun, 10, 2019
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6J1Y
 | | Semi-open conformation E3 ligase | | 分子名称: | GLYCEROL, NEDD4-like E3 ubiquitin-protein ligase WWP1 | | 著者 | Liu, Z.H. | | 登録日 | 2018-12-30 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Nat Commun, 10, 2019
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7KDE
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8HK7
 | | Structure of PKD2-F604P (Polycystin-2, TRPP2) with ML-SA1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, CALCIUM ION, ... | | 著者 | Chen, M.Y, Su, Q, Wang, Z.F, Yu, Y. | | 登録日 | 2022-11-25 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6J1Z
 | | WWP2 semi-open conformation | | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2 | | 著者 | Liu, Z.H. | | 登録日 | 2018-12-30 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Nat Commun, 10, 2019
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8GYX
 | | Cryo-EM structure of human CEPT1 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION | | 著者 | Qian, H.W, Wang, Z.H. | | 登録日 | 2022-09-24 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Nat Commun, 14, 2023
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8GYW
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8HN6
 | | Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD | | 分子名称: | Heavy chain of monoclonal antibody 3G10, Light chain of monoclonal antibody 3G10, Spike protein S1 | | 著者 | Qi, J, Chen, Y. | | 登録日 | 2022-12-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents.
Front Immunol, 14, 2023
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8HN7
 | | Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 3C11, Light chain of monoclonal antibody 3C11, ... | | 著者 | Qi, J, Chen, Y. | | 登録日 | 2022-12-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents.
Front Immunol, 14, 2023
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6IR2
 | | Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM2 at 1.4 Angstron resolution | | 分子名称: | MCherry fluorescent protein, mCherry's nanobody LaM2 | | 著者 | Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X. | | 登録日 | 2018-11-09 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.393 Å) | | 主引用文献 | Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry.
Protein Sci., 30, 2021
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6IR1
 | | Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM4 at 1.9 Angstron resolution | | 分子名称: | MCherry fluorescent protein, mCherry's nanobody LaM4 | | 著者 | Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X. | | 登録日 | 2018-11-09 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.919 Å) | | 主引用文献 | Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry.
Protein Sci., 30, 2021
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