7UAQ

Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement

Summary for 7UAQ

• Entry DOI: 10.2210/pdb7uaq/pdb
• EMDB information: 26430
• Descriptor: Spike glycoprotein, C1520 Fab Heavy Chain, C1520 Fab Light Chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2, n-terminal domain, ntd, neutralizing antibody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2,2019-nCoV); More
• Total number of polymer chains: 3
• Total formula weight: 189793.02

Authors

Barnes, C.O. (deposition date: 2022-03-13, release date: 2022-04-27, Last modification date: 2022-06-22)

• Primary citation: Wang, Z.,Muecksch, F.,Cho, A.,Gaebler, C.,Hoffmann, H.H.,Ramos, V.,Zong, S.,Cipolla, M.,Johnson, B.,Schmidt, F.,DaSilva, J.,Bednarski, E.,Ben Tanfous, T.,Raspe, R.,Yao, K.,Lee, Y.E.,Chen, T.,Turroja, M.,Milard, K.G.,Dizon, J.,Kaczynska, A.,Gazumyan, A.,Oliveira, T.Y.,Rice, C.M.,Caskey, M.,Bieniasz, P.D.,Hatziioannou, T.,Barnes, C.O.,Nussenzweig, M.C.; Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.; Immunity, 55:998-1012.e8, 2022; PubMed: 35447092; DOI: 10.1016/j.immuni.2022.04.003

Experimental method

ELECTRON MICROSCOPY (3.1 Å)