8GYW

Cryo-EM structure of human CEPT1 complexed with CDP-choline

Summary for 8GYW

Entry DOI	10.2210/pdb8gyw/pdb
EMDB information	34378
Descriptor	Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM (3 entities in total)
Functional Keywords	cept1, choline/ethanolamine phosphotransferase, lipid binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	86464.05
Authors	Qian, H.W.,Wang, Z.H. (deposition date: 2022-09-24, release date: 2023-03-22, Last modification date: 2023-10-04)
Primary citation	Wang, Z.,Yang, M.,Yang, Y.,He, Y.,Qian, H. Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1. Nat Commun, 14:2529-2529, 2023 Cited by PubMed: 37137909 DOI: 10.1038/s41467-023-38290-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation