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4L9K

X-ray study of human serum albumin complexed with camptothecin

Summary for 4L9K
Entry DOI10.2210/pdb4l9k/pdb
Related4L8U 4L9Q 4LA0 4LB2 4LB9
DescriptorSERUM ALBUMIN, (2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]butanoic acid (3 entities in total)
Functional Keywordsplasma protein, cancer, oncology drug complex, transport protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02768
Total number of polymer chains2
Total formula weight133875.17
Authors
Wang, Z.,Ho, J.X.,Ruble, J.,Rose, J.P.,Carter, D.C. (deposition date: 2013-06-18, release date: 2013-07-24, Last modification date: 2013-10-23)
Primary citationWang, Z.M.,Ho, J.X.,Ruble, J.R.,Rose, J.,Ruker, F.,Ellenburg, M.,Murphy, R.,Click, J.,Soistman, E.,Wilkerson, L.,Carter, D.C.
Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830:5356-5374, 2013
Cited by
PubMed: 23838380
DOI: 10.1016/j.bbagen.2013.06.032
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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