4L9K
X-ray study of human serum albumin complexed with camptothecin
Summary for 4L9K
Entry DOI | 10.2210/pdb4l9k/pdb |
Related | 4L8U 4L9Q 4LA0 4LB2 4LB9 |
Descriptor | SERUM ALBUMIN, (2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]butanoic acid (3 entities in total) |
Functional Keywords | plasma protein, cancer, oncology drug complex, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02768 |
Total number of polymer chains | 2 |
Total formula weight | 133875.17 |
Authors | Wang, Z.,Ho, J.X.,Ruble, J.,Rose, J.P.,Carter, D.C. (deposition date: 2013-06-18, release date: 2013-07-24, Last modification date: 2013-10-23) |
Primary citation | Wang, Z.M.,Ho, J.X.,Ruble, J.R.,Rose, J.,Ruker, F.,Ellenburg, M.,Murphy, R.,Click, J.,Soistman, E.,Wilkerson, L.,Carter, D.C. Structural studies of several clinically important oncology drugs in complex with human serum albumin. Biochim.Biophys.Acta, 1830:5356-5374, 2013 Cited by PubMed: 23838380DOI: 10.1016/j.bbagen.2013.06.032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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