7KDE

BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195

Summary for 7KDE

• Entry DOI: 10.2210/pdb7kde/pdb
• EMDB information: 22820
• Descriptor: HIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp41, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (17 entities in total)
• Functional Keywords: hiv-1, broadly neutralizing antibody, env, envelope, bg505, bnab, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1 (HIV-1); More
• Total number of polymer chains: 18
• Total formula weight: 533188.53

Authors

Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-10-08, release date: 2020-10-28, Last modification date: 2020-11-04)

• Primary citation: Wang, Z.,Barnes, C.O.,Gautam, R.,Cetrulo Lorenzi, J.C.,Mayer, C.T.,Oliveira, T.Y.,Ramos, V.,Cipolla, M.,Gordon, K.M.,Gristick, H.B.,West, A.P.,Nishimura, Y.,Raina, H.,Seaman, M.S.,Gazumyan, A.,Martin, M.,Bjorkman, P.J.,Nussenzweig, M.C.,Escolano, A.; A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.; Elife, 9:-, 2020; PubMed: 33084569; DOI: 10.7554/eLife.61991

Experimental method

ELECTRON MICROSCOPY (3.55 Å)