7D3D
Crystal structure of SPOP bound with a peptide
Summary for 7D3D
Entry DOI | 10.2210/pdb7d3d/pdb |
Descriptor | Speckle-type POZ protein, GLU-VAL-SER-ILE-ILE-GLN-GLY-ALA-ASP-SER-THR-THR, GLYCEROL, ... (4 entities in total) |
Functional Keywords | ccrcc, e3 ligase adaptor spop, ubiquitination, sbc motif(f-ps-s/t-s/t;f is nonpolar, p is polar), protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 34815.87 |
Authors | Yang, C.-G.,Gan, J.H. (deposition date: 2020-09-18, release date: 2020-11-18, Last modification date: 2023-11-29) |
Primary citation | Wang, Z.,Zhang, H.,Chen, B.,Ouyang, T.,Zheng, T.,Zhou, R.,Dong, Z.,Huang, Y.,Zhang, T.,Jiang, H.,Gan, J.,Luo, C.,Yang, C.-G. A peptide binder of E3 ligase adaptor SPOP disrupts oncogenic SPOP-protein interactions in kidney cancer cells. Chin.J.Chem., 39:271-280, 2021 Cited by DOI: 10.1002/cjoc.202000462PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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