7UAP

Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1520

Summary for 7UAP

Entry DOI	10.2210/pdb7uap/pdb
EMDB information	26429
Descriptor	Spike glycoprotein, C1520 Fab Heavy Chain, C1520 Fab Light Chain, ... (5 entities in total)
Functional Keywords	sars-cov-2, n-terminal domain, ntd, neutralizing antibody, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	9
Total formula weight	575740.04
Authors	Barnes, C.O. (deposition date: 2022-03-13, release date: 2022-04-27, Last modification date: 2022-06-22)
Primary citation	Wang, Z.,Muecksch, F.,Cho, A.,Gaebler, C.,Hoffmann, H.H.,Ramos, V.,Zong, S.,Cipolla, M.,Johnson, B.,Schmidt, F.,DaSilva, J.,Bednarski, E.,Ben Tanfous, T.,Raspe, R.,Yao, K.,Lee, Y.E.,Chen, T.,Turroja, M.,Milard, K.G.,Dizon, J.,Kaczynska, A.,Gazumyan, A.,Oliveira, T.Y.,Rice, C.M.,Caskey, M.,Bieniasz, P.D.,Hatziioannou, T.,Barnes, C.O.,Nussenzweig, M.C. Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins. Immunity, 55:998-1012.e8, 2022 Cited by PubMed: 35447092 DOI: 10.1016/j.immuni.2022.04.003 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation