4LA0

X-ray study of human serum albumin complexed with bicalutamide

Summary for 4LA0

• Entry DOI: 10.2210/pdb4la0/pdb
• Related: 4L8U 4L9K 4L9Q 4LA0 4LB2 4LB9
• Descriptor: SERUM ALBUMIN, R-BICALUTAMIDE (3 entities in total)
• Functional Keywords: plasma protein, cancer, oncology drug complex, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02768
• Total number of polymer chains: 2
• Total formula weight: 134003.18

Authors

Wang, Z.,Ho, J.X.,Ruble, J.,Rose, J.P.,Carter, D.C. (deposition date: 2013-06-18, release date: 2013-07-24, Last modification date: 2014-02-19)

• Primary citation: Wang, Z.M.,Ho, J.X.,Ruble, J.R.,Rose, J.,Ruker, F.,Ellenburg, M.,Murphy, R.,Click, J.,Soistman, E.,Wilkerson, L.,Carter, D.C.; Structural studies of several clinically important oncology drugs in complex with human serum albumin.; Biochim.Biophys.Acta, 1830:5356-5374, 2013; PubMed: 23838380; DOI: 10.1016/j.bbagen.2013.06.032

Experimental method

X-RAY DIFFRACTION (2.4 Å)