4RNC
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![BU of 4rnc by Molmil](/molmil-images/mine/4rnc) | Crystal structure of an esterase RhEst1 from Rhodococcus sp. ECU1013 | 分子名称: | Esterase, PHOSPHATE ION | 著者 | Dou, S, Kong, X.D, Xu, J.H, Zhou, J. | 登録日 | 2014-10-23 | 公開日 | 2015-10-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Substrate channel evolution of an esterase for the synthesis of Cilastatin CATALYSIS SCIENCE AND TECHNOLOGY, 5, 2015
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4TUG
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![BU of 4tug by Molmil](/molmil-images/mine/4tug) | Crystal structure of MjMre11-DNA2 complex | 分子名称: | DNA (5'-D(P*CP*TP*GP*TP*CP*CP*TP*AP*CP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(P*GP*CP*AP*CP*GP*TP*AP*GP*GP*AP*CP*AP*GP*C)-3'), DNA double-strand break repair protein Mre11, ... | 著者 | Sung, S, Cho, Y. | 登録日 | 2014-06-24 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA. Embo J., 33, 2014
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4TUI
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![BU of 4tui by Molmil](/molmil-images/mine/4tui) | Crystal structure of MjMre11-DNA1 complex | 分子名称: | DNA (5'-D(P*TP*CP*CP*TP*AP*CP*GP*TP*GP*CP*CP*AP*G)-3'), DNA (5'-D(P*TP*GP*GP*CP*AP*CP*GP*TP*AP*GP*GP*AP*C)-3'), DNA double-strand break repair protein Mre11 | 著者 | Sung, S, Cho, Y. | 登録日 | 2014-06-24 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA. Embo J., 33, 2014
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6MX8
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![BU of 6mx8 by Molmil](/molmil-images/mine/6mx8) | Crystal structure of anaplastic lymphoma kinase (ALK) bound by Brigatinib | 分子名称: | 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor | 著者 | Dougan, D.R, Zhou, T. | 登録日 | 2018-10-30 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase. J. Med. Chem., 59, 2016
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7C1L
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![BU of 7c1l by Molmil](/molmil-images/mine/7c1l) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant R148A in complex with C8-CoA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1U
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![BU of 7c1u by Molmil](/molmil-images/mine/7c1u) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140V/R148A in a "product-released" conformation | 分子名称: | Non-ribosomal peptide synthetase modules | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1R
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![BU of 7c1r by Molmil](/molmil-images/mine/7c1r) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140A/R148A in complex with C8-CoA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1H
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![BU of 7c1h by Molmil](/molmil-images/mine/7c1h) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA | 分子名称: | Non-ribosomal peptide synthetase modules | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-04 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1S
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![BU of 7c1s by Molmil](/molmil-images/mine/7c1s) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140A/R148A in complex with C8-CoA and Leu-SNAC | 分子名称: | Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A, S-(2-acetamidoethyl) (2S)-2-azanyl-4-methyl-pentanethioate | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1P
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![BU of 7c1p by Molmil](/molmil-images/mine/7c1p) | Crystal structure of the starter condensation domain of the rhizomide synthetase RzmA mutant H140V, R148A | 分子名称: | Non-ribosomal peptide synthetase modules | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D. | 登録日 | 2020-05-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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7C1K
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![BU of 7c1k by Molmil](/molmil-images/mine/7c1k) | Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant R148A | 分子名称: | Non-ribosomal peptide synthetase modules | 著者 | Zhong, L, Diao, X, Zhang, N, Li, F.W, Zhou, H.B, Chen, H.N, Ren, X, Zhang, Y, Wu, D, Bian, X. | 登録日 | 2020-05-04 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.755 Å) | 主引用文献 | Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12, 2021
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3V53
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![BU of 3v53 by Molmil](/molmil-images/mine/3v53) | Crystal structure of human RBM25 | 分子名称: | RNA-binding protein 25 | 著者 | Gong, D.S. | 登録日 | 2011-12-16 | 公開日 | 2012-12-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region Biochem.J., 450, 2013
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6AGG
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![BU of 6agg by Molmil](/molmil-images/mine/6agg) | |
2LN0
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![BU of 2ln0 by Molmil](/molmil-images/mine/2ln0) | Structure of MOZ | 分子名称: | Histone acetyltransferase KAT6A, ZINC ION | 著者 | Qiu, Y. | 登録日 | 2011-12-15 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription. Genes Dev., 26, 2012
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6IZ5
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![BU of 6iz5 by Molmil](/molmil-images/mine/6iz5) | |
6CDX
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![BU of 6cdx by Molmil](/molmil-images/mine/6cdx) | High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin | 分子名称: | cystine knot (fluoropropylated) | 著者 | Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V. | 登録日 | 2018-02-09 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nat Commun, 10, 2019
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6CKC
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![BU of 6ckc by Molmil](/molmil-images/mine/6ckc) | Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity | 分子名称: | 7-[(5R)-5-C-phenyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Methylosome protein 50, Protein arginine N-methyltransferase 5 | 著者 | Antonysamy, S. | 登録日 | 2018-02-27 | 公開日 | 2018-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med Chem Lett, 9, 2018
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6CHH
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![BU of 6chh by Molmil](/molmil-images/mine/6chh) | Structure of human NNMT in complex with bisubstrate inhibitor MS2756 | 分子名称: | (2~{S})-5-[2-(3-aminocarbonylphenyl)ethyl-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]amino]-2-azanyl-pentanoic acid, 1,2-ETHANEDIOL, Nicotinamide N-methyltransferase | 著者 | Babault, N, Liu, J, Jin, J. | 登録日 | 2018-02-22 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT). J. Med. Chem., 61, 2018
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6IYX
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![BU of 6iyx by Molmil](/molmil-images/mine/6iyx) | Crystal Structure Analysis of a Eukaryotic Membrane Protein | 分子名称: | BROMIDE ION, CALCIUM ION, Trimeric intracellular cation channel type A | 著者 | Zeng, Y, Wang, X.H, Gao, F, Su, M, Chen, Y.H. | 登録日 | 2018-12-17 | 公開日 | 2019-05-01 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IYZ
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![BU of 6iyz by Molmil](/molmil-images/mine/6iyz) | Structural basis for activity of TRIC counter-ion channels in calcium release | 分子名称: | CHLORIDE ION, Trimeric intracellular cation channel type A | 著者 | Wang, X.H, Zeng, Y, Qin, L, Gao, F, Su, M, Chen, Y.H. | 登録日 | 2018-12-18 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IZ4
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![BU of 6iz4 by Molmil](/molmil-images/mine/6iz4) | Crystal Structure Analysis of TRIC counter-ion channels in calcium release | 分子名称: | Trimeric intracellular cation channel type B-B | 著者 | Wang, X.H, Zeng, Y, Gao, F, Su, M, Hendrickson, W.A, Chen, Y.H. | 登録日 | 2018-12-18 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.098 Å) | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IYU
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![BU of 6iyu by Molmil](/molmil-images/mine/6iyu) | Crystal Structure Analysis of an Eukaryotic Membrane Protein | 分子名称: | CALCIUM ION, CHLORIDE ION, Trimeric intracellular cation channel type A | 著者 | Wang, X.H, Zeng, Y, Su, M, Gao, F, Chen, Y.H. | 登録日 | 2018-12-17 | 公開日 | 2019-05-01 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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6IZ1
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![BU of 6iz1 by Molmil](/molmil-images/mine/6iz1) | Crystal Structure Analysis of a Eukaryotic Membrane Protein | 分子名称: | CALCIUM ION, CHLORIDE ION, Trimeric intracellular cation channel type A | 著者 | Wang, X.H, Zeng, Y, Gao, F, Su, M, Chen, Y.H. | 登録日 | 2018-12-18 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
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5OJH
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![BU of 5ojh by Molmil](/molmil-images/mine/5ojh) | Crystal structure of the extramembrane domain of the cellulose biosynthetic protein BcsG from Salmonella typhimurium | 分子名称: | CITRATE ANION, Cellulose biosynthesis protein BcsG, ZINC ION | 著者 | Schneider, G, Vella, P, Lindqvist, Y, Schnell, R. | 登録日 | 2017-07-21 | 公開日 | 2018-08-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium. J. Mol. Biol., 430, 2018
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5OLT
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![BU of 5olt by Molmil](/molmil-images/mine/5olt) | Crystal structure of the extramembrane domain of the cellulose biosynthetic protein BcsG from Salmonella typhimurium | 分子名称: | CITRIC ACID, Cellulose biosynthesis protein BcsG, ZINC ION | 著者 | Vella, P, Polyakova, A, Lindqvist, Y, Schnell, R, Bourenkov, G, Schneider, T, Schneider, G. | 登録日 | 2017-07-28 | 公開日 | 2018-08-08 | 最終更新日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium. J. Mol. Biol., 430, 2018
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