7KBB

Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21

Summary for 7KBB

• Entry DOI: 10.2210/pdb7kbb/pdb
• EMDB information: 22788
• Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, Envelope protein UL128, ... (7 entities in total)
• Functional Keywords: hcmv pentamer, fab, complex, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 7
• Total formula weight: 149161.34

Authors

Wrapp, D.,McLellan, J.S. (deposition date: 2020-10-01, release date: 2021-08-11, Last modification date: 2022-03-23)

• Primary citation: Wrapp, D.,Ye, X.,Ku, Z.,Su, H.,Jones, H.G.,Wang, N.,Mishra, A.K.,Freed, D.C.,Li, F.,Tang, A.,Li, L.,Jaijyan, D.K.,Zhu, H.,Wang, D.,Fu, T.M.,Zhang, N.,An, Z.,McLellan, J.S.; Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.; Sci Adv, 8:eabm2546-eabm2546, 2022; PubMed: 35275718; DOI: 10.1126/sciadv.abm2546

Experimental method

ELECTRON MICROSCOPY (4.02 Å)