7KBA

Crystal structure of the HCMV pentamer-specific Fab 2-18

Summary for 7KBA

Entry DOI	10.2210/pdb7kba/pdb
Descriptor	2-18 Fab Heavy Chain, 2-18 Fab Light Chain (3 entities in total)
Functional Keywords	antibody, hcmv, fab, antiviral protein, immune system
Biological source	Homo sapiens More
Total number of polymer chains	4
Total formula weight	98073.09
Authors	Wrapp, D.,McLellan, J.S. (deposition date: 2020-10-01, release date: 2021-08-11, Last modification date: 2023-10-18)
Primary citation	Wrapp, D.,Ye, X.,Ku, Z.,Su, H.,Jones, H.G.,Wang, N.,Mishra, A.K.,Freed, D.C.,Li, F.,Tang, A.,Li, L.,Jaijyan, D.K.,Zhu, H.,Wang, D.,Fu, T.M.,Zhang, N.,An, Z.,McLellan, J.S. Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8:eabm2546-eabm2546, 2022 Cited by PubMed: 35275718 DOI: 10.1126/sciadv.abm2546 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation