7BZF
| COVID-19 RNA-dependent RNA polymerase post-translocated catalytic complex | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA (31-MER), ... | 著者 | Wang, Q, Gao, Y, Ji, W, Mu, A, Rao, Z. | 登録日 | 2020-04-27 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. Cell, 182, 2020
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7BVE
| Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol | 分子名称: | CALCIUM ION, Ethambutol, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, ... | 著者 | Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. | 登録日 | 2020-04-10 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-01 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
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7BX8
| Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric "resting state" | 分子名称: | Integral membrane indolylacetylinositol arabinosyltransferase EmbB, Meromycolate extension acyl carrier protein | 著者 | Gao, R.G, Zhang, L, Wang, Q, Rao, Z.H. | 登録日 | 2020-04-17 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2. Protein Cell, 11, 2020
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7BTF
| SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-04-01 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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7BVG
| Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. | 分子名称: | 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ... | 著者 | Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z. | 登録日 | 2020-04-10 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
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7BWR
| Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric "active state" | 分子名称: | CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbB, Meromycolate extension acyl carrier protein, ... | 著者 | Gao, R.G, Zhang, L, Wang, Q, Rao, Z.H. | 登録日 | 2020-04-15 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2. Protein Cell, 11, 2020
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7C2M
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with NITD-349 | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Chimera of drug exporters of the RND superfamily-like protein and Endolysin, N-(4,4-dimethylcyclohexyl)-4,6-bis(fluoranyl)-1H-indole-2-carboxamide, ... | 著者 | Zhang, B, Yang, X, Hu, T, Rao, Z. | 登録日 | 2020-05-08 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO. J.Mol.Biol., 432, 2020
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7C2K
| COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA (29-MER), ... | 著者 | Wang, Q, Gao, Y, Ji, W, Mu, A, Rao, Z. | 登録日 | 2020-05-07 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. Cell, 182, 2020
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7CAF
| Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | 登録日 | 2020-06-08 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7C2N
| Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SPIRO | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1'-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)spiro[6,7-dihydrothieno[3,2-c]pyran-4,4'-piperidine], Drug exporters of the RND superfamily-like protein,Endolysin, ... | 著者 | Zhang, B, Yang, X, Hu, T, Rao, Z. | 登録日 | 2020-05-08 | 公開日 | 2020-12-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO. J.Mol.Biol., 432, 2020
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7CAG
| Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T. | 登録日 | 2020-06-08 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CAD
| Mycobacterium smegmatis SugABC complex | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | 登録日 | 2020-06-08 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CAE
| Mycobacterium smegmatis LpqY-SugABC complex in the resting state | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | 登録日 | 2020-06-08 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CYQ
| Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... | 著者 | Yan, L, Ge, J, Zheng, L, Zhang, Y, Gao, Y, Wang, T, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | 登録日 | 2020-09-04 | 公開日 | 2020-12-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. Cell, 184, 2021
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7D6V
| Mycobacterium smegmatis Sdh1 in complex with UQ1 | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Zhou, X, Gao, Y, Wang, Q, Gong, H, Rao, Z. | 登録日 | 2020-10-02 | 公開日 | 2021-04-07 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster. Proc.Natl.Acad.Sci.USA, 118, 2021
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7D6X
| Mycobacterium smegmatis Sdh1 complex in the apo form | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Zhou, X, Gao, Y, Wang, Q, Gong, H, Rao, Z. | 登録日 | 2020-10-02 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster. Proc.Natl.Acad.Sci.USA, 118, 2021
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7D7L
| The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155 | 分子名称: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, CAFFEINE, GLYCEROL, ... | 著者 | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | 登録日 | 2020-10-04 | 公開日 | 2021-04-21 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell, 12, 2021
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7D7K
| The crystal structure of SARS-CoV-2 papain-like protease in apo form | 分子名称: | 1,2-ETHANEDIOL, CAFFEINE, Non-structural protein 3, ... | 著者 | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | 登録日 | 2020-10-04 | 公開日 | 2021-04-21 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell, 12, 2021
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7D5I
| Structure of Mycobacterium smegmatis bd complex in the apo-form. | 分子名称: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome D ubiquinol oxidase subunit 1, HEME B/C, ... | 著者 | Wang, W, Gong, H, Gao, Y, Zhou, X, Rao, Z. | 登録日 | 2020-09-26 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels. Nat Commun, 12, 2021
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7CY2
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7CZ2
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7CYR
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7BUY
| The crystal structure of COVID-19 main protease in complex with carmofur | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, hexylcarbamic acid | 著者 | Zhao, Y, Zhang, B, Jin, Z, Liu, X, Yang, H, Rao, Z. | 登録日 | 2020-04-08 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Nat.Struct.Mol.Biol., 27, 2020
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7BVH
| Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose | 分子名称: | CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, ... | 著者 | Zhao, Y, Zhang, L, Wu, L.J, Wang, Q, Li, J, Besra, G.S, Rao, Z.H. | 登録日 | 2020-04-10 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
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7BQY
| THE CRYSTAL STRUCTURE OF COVID-19 MAIN PROTEASE IN COMPLEX WITH AN INHIBITOR N3 at 1.7 angstrom | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | 著者 | Liu, X, Zhang, B, Jin, Z, Yang, H, Rao, Z. | 登録日 | 2020-03-26 | 公開日 | 2020-04-22 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of Mprofrom SARS-CoV-2 and discovery of its inhibitors. Nature, 582, 2020
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