7D7L

The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155

Summary for 7D7L

• Entry DOI: 10.2210/pdb7d7l/pdb
• Descriptor: Non-structural protein 3, ZINC ION, CAFFEINE, ... (7 entities in total)
• Functional Keywords: protease, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 2
• Total formula weight: 73924.90

Authors

Zhao, Y.,Sun, L.,Yang, H.T.,Rao, Z.H. (deposition date: 2020-10-04, release date: 2021-04-21, Last modification date: 2021-11-17)

• Primary citation: Zhao, Y.,Du, X.,Duan, Y.,Pan, X.,Sun, Y.,You, T.,Han, L.,Jin, Z.,Shang, W.,Yu, J.,Guo, H.,Liu, Q.,Wu, Y.,Peng, C.,Wang, J.,Zhu, C.,Yang, X.,Yang, K.,Lei, Y.,Guddat, L.W.,Xu, W.,Xiao, G.,Sun, L.,Zhang, L.,Rao, Z.,Yang, H.; High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.; Protein Cell, 12:877-888, 2021; PubMed: 33864621; DOI: 10.1007/s13238-021-00836-9

Experimental method

X-RAY DIFFRACTION (2.11 Å)