7D7L
The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Non-structural protein 3 | polymer | 312 | 35270.0 | 2 | UniProt (P0DTD1) Pfam (PF08715) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | nsp3, PL2-PRO, Papain-like protease, Papain-like proteinase, PL-PRO |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | CAFFEINE | non-polymer | 194.2 | 2 | Chemie (CFF) | |||
| 4 | A, B | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione | non-polymer | 363.4 | 5 | Chemie (GXU) | |||
| 5 | A, B | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 6 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 419 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 315 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 111 | Cys 1674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70540.0 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 3384.9 | |
| All* | Total formula weight | 73924.9 |
