COVID-19 RNA-dependent RNA polymerase post-translocated catalytic complex

Summary for 7BZF

EMDB information30252
DescriptorRNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (6 entities in total)
Functional Keywordscovid-19, 2019-ncov, sars-cov-2, virus, rdrp, nsp12, nsp7, nsp8, rtc, cryo-em, viral protein, rna polymerase, drug target, antiviral, replication transcription complex, viral protein-rna complex, viral protein/rna
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains6
Total molecular weight175832.92
Wang, Q.,Gao, Y.,Ji, W.,Mu, A.,Rao, Z. (deposition date: 2020-04-27, release date: 2020-06-03, Last modification date: 2020-08-05)
Primary citation
Wang, Q.,Wu, J.,Wang, H.,Gao, Y.,Liu, Q.,Mu, A.,Ji, W.,Yan, L.,Zhu, Y.,Zhu, C.,Fang, X.,Yang, X.,Huang, Y.,Gao, H.,Liu, F.,Ge, J.,Sun, Q.,Yang, X.,Xu, W.,Liu, Z.,Yang, H.,Lou, Z.,Jiang, B.,Guddat, L.W.,Gong, P.,Rao, Z.
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Cell, 182:417-428.e13, 2020
PubMed: 32526208 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2020.05.034
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone1100 0.59MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-12-02