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7BVH

Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose

Summary for 7BVH
Entry DOI10.2210/pdb7bvh/pdb
Related PRD IDPRD_900018
DescriptorIntegral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, alpha-D-arabinofuranose-(1-5)-alpha-D-arabinofuranose, ... (7 entities in total)
Functional Keywordscell wall synthesis, arabinosyltransferase, drug target, transferase
Biological sourceMycolicibacterium smegmatis MC2 155
More
Total number of polymer chains4
Total formula weight264975.47
Authors
Zhao, Y.,Zhang, L.,Wu, L.J.,Wang, Q.,Li, J.,Besra, G.S.,Rao, Z.H. (deposition date: 2020-04-10, release date: 2020-04-29, Last modification date: 2020-07-29)
Primary citationZhang, L.,Zhao, Y.,Gao, Y.,Wu, L.,Gao, R.,Zhang, Q.,Wang, Y.,Wu, C.,Wu, F.,Gurcha, S.S.,Veerapen, N.,Batt, S.M.,Zhao, W.,Qin, L.,Yang, X.,Wang, M.,Zhu, Y.,Zhang, B.,Bi, L.,Zhang, X.,Yang, H.,Guddat, L.W.,Xu, W.,Wang, Q.,Li, J.,Besra, G.S.,Rao, Z.
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368:1211-1219, 2020
Cited by
PubMed: 32327601
DOI: 10.1126/science.aba9102
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.3 Å)
Structure validation

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