7BUY
The crystal structure of COVID-19 main protease in complex with carmofur
Summary for 7BUY
Entry DOI | 10.2210/pdb7buy/pdb |
Descriptor | 3C-like proteinase, hexylcarbamic acid, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | covid-2019 virus, main protease, carmofur, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 1 |
Total formula weight | 34361.41 |
Authors | |
Primary citation | Jin, Z.,Zhao, Y.,Sun, Y.,Zhang, B.,Wang, H.,Wu, Y.,Zhu, Y.,Zhu, C.,Hu, T.,Du, X.,Duan, Y.,Yu, J.,Yang, X.,Yang, X.,Yang, K.,Liu, X.,Guddat, L.W.,Xiao, G.,Zhang, L.,Yang, H.,Rao, Z. Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur. Nat.Struct.Mol.Biol., 27:529-532, 2020 Cited by PubMed: 32382072DOI: 10.1038/s41594-020-0440-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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