2M3I
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![BU of 2m3i by Molmil](/molmil-images/mine/2m3i) | Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors | Descriptor: | Alpha-conotoxin | Authors: | Luo, S, Zhangsun, D, Zhu, X, Wu, Y, Hu, Y, Christensen, S, Akcan, M, Craik, D.J, McIntosh, J.M. | Deposit date: | 2013-01-20 | Release date: | 2013-12-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors. J.Med.Chem., 56, 2013
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2M79
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![BU of 2m79 by Molmil](/molmil-images/mine/2m79) | [Asp2,11]RTD-1 | Descriptor: | [Asp2,11]RTD-1 | Authors: | Conibear, A.C, Bochen, A, Rosengren, K, Kessler, H, Craik, D.J. | Deposit date: | 2013-04-19 | Release date: | 2014-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Cyclic Cystine Ladder of Theta-Defensins as a Stable, Bifunctional Scaffold: A Proof-of-Concept Study Using the Integrin-Binding RGD Motif Chembiochem, 15, 2014
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2MP8
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![BU of 2mp8 by Molmil](/molmil-images/mine/2mp8) | NMR structure of NKR-5-3B | Descriptor: | NKR-5-3B | Authors: | Rosengren, K.J, Craik, D.J. | Deposit date: | 2014-05-13 | Release date: | 2015-05-13 | Last modified: | 2016-06-01 | Method: | SOLUTION NMR | Cite: | Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium Biochemistry, 54, 2015
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2N2R
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![BU of 2n2r by Molmil](/molmil-images/mine/2n2r) | NMR solution structure of RsAFP2 | Descriptor: | Defensin-like protein 2 | Authors: | Harvey, P.J, Craik, D.J, Vriens, K. | Deposit date: | 2015-05-12 | Release date: | 2016-05-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin against Candida albicans biofilms. Peptides, 75, 2016
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2N2Q
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![BU of 2n2q by Molmil](/molmil-images/mine/2n2q) | NMR solution structure of HsAFP1 | Descriptor: | Defensin-like protein 1 | Authors: | Harvey, P.J, Craik, D.J, Vriens, K. | Deposit date: | 2015-05-11 | Release date: | 2015-07-22 | Last modified: | 2015-08-19 | Method: | SOLUTION NMR | Cite: | Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures. Plos One, 10, 2015
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2PO8
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![BU of 2po8 by Molmil](/molmil-images/mine/2po8) | |
2RU2
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![BU of 2ru2 by Molmil](/molmil-images/mine/2ru2) | |
8FEG
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![BU of 8feg by Molmil](/molmil-images/mine/8feg) | CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1 | Descriptor: | ACE-TYR-ALA-DTY-THR-THR-CYS-THR-DPN-XT9, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Fay, J.F, Che, T. | Deposit date: | 2022-12-06 | Release date: | 2023-12-06 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nat Commun, 14, 2023
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5WOV
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![BU of 5wov by Molmil](/molmil-images/mine/5wov) | |
5WE3
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![BU of 5we3 by Molmil](/molmil-images/mine/5we3) | Solution NMR structure of PaurTx-3 | Descriptor: | Beta-theraphotoxin-Ps1a | Authors: | Agwa, A.J, Schroeder, C.I. | Deposit date: | 2017-07-06 | Release date: | 2017-09-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins. Toxins (Basel), 9, 2017
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5WOW
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3E4H
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![BU of 3e4h by Molmil](/molmil-images/mine/3e4h) | Crystal structure of the cyclotide varv F | Descriptor: | Varv peptide F,Varv peptide F | Authors: | Hu, S.H. | Deposit date: | 2008-08-11 | Release date: | 2009-02-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold J.Biol.Chem., 284, 2009
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4NE9
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![BU of 4ne9 by Molmil](/molmil-images/mine/4ne9) | PCSK9 in complex with LDLR peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low-density lipoprotein receptor, ... | Authors: | Liu, S. | Deposit date: | 2013-10-28 | Release date: | 2014-09-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chem.Biol., 21, 2014
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2BC8
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![BU of 2bc8 by Molmil](/molmil-images/mine/2bc8) | [Sec2,3,8,12]-ImI | Descriptor: | Alpha-conotoxin ImI | Authors: | Armishaw, C.J. | Deposit date: | 2005-10-18 | Release date: | 2006-03-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | {alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists. J.Biol.Chem., 281, 2006
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2BC7
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![BU of 2bc7 by Molmil](/molmil-images/mine/2bc7) | Solution structure of [Sec2,8]-ImI | Descriptor: | Alpha-conotoxin ImI | Authors: | Armishaw, C.J. | Deposit date: | 2005-10-18 | Release date: | 2006-03-14 | Last modified: | 2014-08-06 | Method: | SOLUTION NMR | Cite: | {alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists. J.Biol.Chem., 281, 2006
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3P8G
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![BU of 3p8g by Molmil](/molmil-images/mine/3p8g) | Crystal Structure of MT-SP1 in complex with benzamidine | Descriptor: | 1,2-ETHANEDIOL, BENZAMIDINE, GLUTATHIONE, ... | Authors: | Yuan, C, Huang, M, Chen, L. | Deposit date: | 2010-10-13 | Release date: | 2011-08-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. Bmc Struct.Biol., 11, 2011
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3P8F
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![BU of 3p8f by Molmil](/molmil-images/mine/3p8f) | |
6MK4
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![BU of 6mk4 by Molmil](/molmil-images/mine/6mk4) | |
6MK5
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![BU of 6mk5 by Molmil](/molmil-images/mine/6mk5) | |
6NOX
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![BU of 6nox by Molmil](/molmil-images/mine/6nox) | Solution structure of SFTI-KLK5 inhibitor | Descriptor: | SFTI-KLK5 Peptide | Authors: | White, A.M. | Deposit date: | 2019-01-16 | Release date: | 2019-04-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases. J. Med. Chem., 62, 2019
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6OTA
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![BU of 6ota by Molmil](/molmil-images/mine/6ota) | |
7RMQ
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![BU of 7rmq by Molmil](/molmil-images/mine/7rmq) | Crystal structure of cycloviolacin O2 | Descriptor: | Cycloviolacin O2, D-[I11L]cycloviolacin O2, FORMIC ACID | Authors: | Huang, Y.H, Du, Q. | Deposit date: | 2021-07-28 | Release date: | 2021-09-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Enabling Efficient Folding and High-Resolution Crystallographic Analysis of Bracelet Cyclotides. Molecules, 26, 2021
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7RJF
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![BU of 7rjf by Molmil](/molmil-images/mine/7rjf) | MOPD-1 mutant-L47W | Descriptor: | MALONATE ION, ZINC ION, [L47W]MOPD-1 | Authors: | Huawu, Y, Conan, K.W, Gordon, J.K, Brett, M.C, Yen-Hua, H, David, J.C. | Deposit date: | 2021-07-20 | Release date: | 2021-10-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. J.Am.Chem.Soc., 143, 2021
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5JI4
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![BU of 5ji4 by Molmil](/molmil-images/mine/5ji4) | Solution structure of the de novo mini protein gEEHE_02 | Descriptor: | W37 | Authors: | Buchko, G.W, Bahl, C.D, Pulavarti, S.V, Baker, D, Szyperski, T. | Deposit date: | 2016-04-21 | Release date: | 2016-09-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
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5JHI
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![BU of 5jhi by Molmil](/molmil-images/mine/5jhi) | Solution structure of the de novo mini protein gEHE_06 | Descriptor: | W35 | Authors: | Buchko, G.W, Bahl, C.D, Gilmore, J.M, Pulavarti, S.V, Baker, D, Szyperski, T. | Deposit date: | 2016-04-21 | Release date: | 2016-09-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
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