7RJF
MOPD-1 mutant-L47W
Summary for 7RJF
Entry DOI | 10.2210/pdb7rjf/pdb |
Descriptor | [L47W]MOPD-1, ZINC ION, MALONATE ION, ... (4 entities in total) |
Functional Keywords | synthetic peptide, disulfide-rich peptide, antitumor peptide, peptide mimetic, antitumor protein |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 11934.23 |
Authors | Huawu, Y.,Conan, K.W.,Gordon, J.K.,Brett, M.C.,Yen-Hua, H.,David, J.C. (deposition date: 2021-07-20, release date: 2021-10-27, Last modification date: 2023-10-18) |
Primary citation | Yin, H.,Zhou, X.,Huang, Y.H.,King, G.J.,Collins, B.M.,Gao, Y.,Craik, D.J.,Wang, C.K. Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. J.Am.Chem.Soc., 143:18536-18547, 2021 Cited by PubMed: 34661406DOI: 10.1021/jacs.1c08132 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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