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5WOW

Solution NMR structure of cyclotide MCoTI-I

Summary for 5WOW
Entry DOI10.2210/pdb5wow/pdb
NMR InformationBMRB: 30324
DescriptorTwo inhibitor peptide topologies 2 (1 entity in total)
Functional Keywordscyclotide, plant peptide, cyclic cystine knot, grafted peptide, bioactive epitope, de novo protein
Biological sourceMomordica cochinchinensis (Spiny bitter cucumber)
Total number of polymer chains1
Total formula weight4247.84
Authors
Schroeder, C.I.,Kwon, S. (deposition date: 2017-08-03, release date: 2018-08-08, Last modification date: 2023-06-14)
Primary citationKwon, S.,Duarte, J.N.,Li, Z.,Ling, J.J.,Cheneval, O.,Durek, T.,Schroeder, C.I.,Craik, D.J.,Ploegh, H.L.
Targeted Delivery of Cyclotides via Conjugation to a Nanobody.
ACS Chem. Biol., 13:2973-2980, 2018
Cited by
PubMed: 30248263
DOI: 10.1021/acschembio.8b00653
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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