2M3I
Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors
Summary for 2M3I
Entry DOI | 10.2210/pdb2m3i/pdb |
NMR Information | BMRB: 18964 |
Descriptor | Alpha-conotoxin (1 entity in total) |
Functional Keywords | alpha-conotoxin, alpha-helix, disulfide bonds, amidated c-terminus, toxin |
Biological source | Conus lividus |
Cellular location | Secreted (By similarity): H9N3R7 |
Total number of polymer chains | 1 |
Total formula weight | 1493.82 |
Authors | Luo, S.,Zhangsun, D.,Zhu, X.,Wu, Y.,Hu, Y.,Christensen, S.,Akcan, M.,Craik, D.J.,McIntosh, J.M. (deposition date: 2013-01-20, release date: 2013-12-04, Last modification date: 2023-06-14) |
Primary citation | Luo, S.,Zhangsun, D.,Zhu, X.,Wu, Y.,Hu, Y.,Christensen, S.,Harvey, P.J.,Akcan, M.,Craik, D.J.,McIntosh, J.M. Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors. J.Med.Chem., 56:9655-9663, 2013 Cited by PubMed: 24200193DOI: 10.1021/jm401254c PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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