Search by PDB author

BOVINE THROMBIN--BM14.1248 COMPLEX
Descriptor:	N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE, THROMBIN
Authors:	Engh, R.A, Huber, R.
Deposit date:	1996-10-16
Release date:	1997-11-19
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. Structure, 4, 1996

1UVS

BOVINE THROMBIN--BM51.1011 COMPLEX
Descriptor:	THROMBIN, [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE
Authors:	Engh, R.A, Huber, R.
Deposit date:	1996-10-16
Release date:	1997-11-19
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. Structure, 4, 1996

1UVU

BOVINE THROMBIN--BM12.1700 COMPLEX
Descriptor:	3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER, THROMBIN
Authors:	Engh, R.A, Huber, R.
Deposit date:	1996-10-16
Release date:	1997-11-19
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. Structure, 4, 1996

3HTC

THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2
Authors:	Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W.
Deposit date:	1993-06-11
Release date:	1994-01-31
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249, 1990

1BTH

STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor:	BOVINE PANCREATIC TRYPSIN INHIBITOR, THROMBIN
Authors:	Van De Locht, A, Bode, W, Stubbs, M.T.
Deposit date:	1996-12-03
Release date:	1997-12-24
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin. EMBO J., 16, 1997

1ABI

STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRULOG 3
Authors:	Qiu, X, Tulinsky, A.
Deposit date:	1992-08-24
Release date:	1994-01-31
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors. Biochemistry, 31, 1992

1ABJ

STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
Authors:	Qiu, X, Tulinsky, A.
Deposit date:	1992-08-24
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors. Biochemistry, 31, 1992

6R9Z

3D NMR solution structure of ligand peptide (Ac)EVNPPVP of Pro-Pro endopeptidase-1
Descriptor:	ACE-GLU-VAL-ASN-PRO-PRO-VAL-PRO-NH2
Authors:	Diaz, D.
Deposit date:	2019-04-04
Release date:	2019-06-19
Last modified:	2019-08-07
Method:	SOLUTION NMR
Cite:	Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1. J.Biol.Chem., 294, 2019

2HGT

STRUCTURE OF THE HIRUGEN AND HIRULOG 1 COMPLEXES OF ALPHA-THROMBIN
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), Hirulog
Authors:	Tulinsky, A, Carperos, V.
Deposit date:	1991-06-03
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structure of the hirugen and hirulog 1 complexes of alpha-thrombin. J.Mol.Biol., 221, 1991

1PPH

GEOMETRY OF BINDING OF THE NALPHA-TOSYLATED PIPERIDIDES OF M-AMIDINO-, P-AMIDINO-AND P-GUANIDINO PHENYLALANINE TO THROMBIN AND TRYPSIN: X-RAY CRYSTAL STRUCTURES OF THEIR TRYPSIN COMPLEXES AND MODELING OF THEIR THROMBIN COMPLEXES
Descriptor:	3-[(2S)-2-{[(4-methylphenyl)sulfonyl]amino}-3-oxo-3-piperidin-1-ylpropyl]benzenecarboximidamide, CALCIUM ION, SULFATE ION, ...
Authors:	Bode, W, Turk, D.
Deposit date:	1991-10-24
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Geometry of binding of the N alpha-tosylated piperidides of m-amidino-, p-amidino- and p-guanidino phenylalanine to thrombin and trypsin. X-ray crystal structures of their trypsin complexes and modeling of their thrombin complexes. FEBS Lett., 287, 1991

1ETT

REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS
Descriptor:	4-[(2S)-2-{[(4-methylphenyl)sulfonyl]amino}-3-oxo-3-(piperidin-1-yl)propyl]benzene-1-carboximidamide, EPSILON-THROMBIN
Authors:	Bode, W, Brandstetter, H.
Deposit date:	1992-07-06
Release date:	1994-01-31
Last modified:	2018-09-12
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992

1ETS

REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS
Descriptor:	1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, EPSILON-THROMBIN
Authors:	Bode, W, Brandstetter, H.
Deposit date:	1992-07-06
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992

1DWB

CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), BENZAMIDINE, ...
Authors:	Banner, D.W, Hadvary, P.
Deposit date:	1992-08-19
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (3.16 Å)
Cite:	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1DWC

CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIA, ...
Authors:	Banner, D.W, Hadvary, P.
Deposit date:	1992-08-19
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1DWD

CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Descriptor:	1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:	Banner, D.W, Hadvary, P.
Deposit date:	1992-08-19
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1G9K

CRYSTAL STRUCTURE OF A PSYCHROPHILIC ALKALINE PROTEASE FROM PSEUDOMONAS TAC II 18
Descriptor:	CALCIUM ION, SERRALYSIN, SULFATE ION, ...
Authors:	Aghajari, N, Haser, R.
Deposit date:	2000-11-24
Release date:	2003-02-14
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (1.96 Å)
Cite:	Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold-adapted proteases Proteins, 50, 2003

1DWE

Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
Descriptor:	ALPHA-THROMBIN heavy chain, ALPHA-THROMBIN light chain, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:	Banner, D.W, Hadvary, P.
Deposit date:	1992-08-19
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors. J.Biol.Chem., 266, 1991

1ETR

REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS
Descriptor:	EPSILON-THROMBIN, amino{[(4S)-5-[(2R,4R)-2-carboxy-4-methylpiperidin-1-yl]-4-({[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}amino)-5-oxopentyl]amino}methaniminium
Authors:	Bode, W, Brandstetter, H.
Deposit date:	1992-07-06
Release date:	1994-01-31
Last modified:	2024-06-05
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics. J.Mol.Biol., 226, 1992

1TOC

STRUCTURE OF SERINE PROTEINASE
Descriptor:	ORNITHODORIN, THROMBIN
Authors:	Van De Locht, A, Huber, R, Bode, W.
Deposit date:	1996-07-20
Release date:	1997-07-23
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	The ornithodorin-thrombin crystal structure, a key to the TAP enigma? EMBO J., 15, 1996

1TBR

CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
Descriptor:	RHODNIIN, THROMBIN
Authors:	Van De Locht, A, Lamba, D, Bode, W.
Deposit date:	1995-03-03
Release date:	1996-10-14
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995

1TMT

CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:	Priestle, J.P, Gruetter, M.G.
Deposit date:	1994-05-26
Release date:	1994-09-30
Last modified:	2022-12-21
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms. Protein Sci., 2, 1993

1TMU

Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Hirudin variant-2, ...
Authors:	Priestle, J.P, Gruetter, M.G.
Deposit date:	1994-05-26
Release date:	1994-09-30
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms. Protein Sci., 2, 1993

1TBQ

CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
Descriptor:	RHODNIIN, THROMBIN
Authors:	Van De Locht, A, Lamba, D, Bode, W.
Deposit date:	1995-03-02
Release date:	1996-10-14
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin. EMBO J., 14, 1995

<1 2 3 4 5 6 78

Total results:	198
Displayed results:	23
Sorted by:	Hit score (from highest)