8WOS
 
 | | Cryo-EM structure of human SIDT1 protein with C1 symmetry at low pH | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | | Deposit date: | 2023-10-07 | | Release date: | 2024-03-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1.
Cell Discov, 10, 2024
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7XVQ
 | | Crystal structure of AcrIIC4 | | Descriptor: | Uncharacterized protein | | Authors: | Zhang, H, Li, X.Z, Song, G.Y. | | Deposit date: | 2022-05-24 | | Release date: | 2023-08-09 | | Last modified: | 2025-02-26 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4.
Nucleic Acids Res., 51, 2023
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7NAB
 | | Crystal structure of human neutralizing mAb CV3-25 binding to SARS-CoV-2 S MPER peptide 1140-1165 | | Descriptor: | CITRIC ACID, CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, ... | | Authors: | Chen, Y, Tolbert, W.D, Pazgier, M. | | Deposit date: | 2021-06-21 | | Release date: | 2021-12-08 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.
Cell Rep, 38, 2022
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7XY7
 | | Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Zhang, J.Y, Chen, Y, Hua, T, Song, G.J. | | Deposit date: | 2022-05-31 | | Release date: | 2023-05-03 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex.
Sci Adv, 8, 2022
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7XY6
 | | Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM | | Descriptor: | 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Zhang, J.Y, Chen, Y, Hua, T, Song, G.J. | | Deposit date: | 2022-05-31 | | Release date: | 2023-05-03 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex.
Sci Adv, 8, 2022
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5IMX
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8JA0
 | | Cryo-EM structure of the NmeCas9-sgRNA-AcrIIC4 ternary complex | | Descriptor: | CRISPR-associated endonuclease Cas9, RNA (117-MER), Uncharacterized protein | | Authors: | Yin, H, Li, Z, Yu, G.M, Li, X.Z. | | Deposit date: | 2023-05-05 | | Release date: | 2023-08-09 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Inhibitory mechanism of CRISPR-Cas9 by AcrIIC4.
Nucleic Acids Res., 51, 2023
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2MKZ
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7EP0
 | | Crystal structure of ZYG11B bound to GSTE degron | | Descriptor: | Protein zyg-11 homolog B, sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) | | Authors: | Yan, X, Li, Y. | | Deposit date: | 2021-04-26 | | Release date: | 2021-07-14 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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7EP3
 | | Crystal structure of ZER1 bound to GAGN degron | | Descriptor: | Protein zer-1 homolog | | Authors: | Yan, X, Li, Y. | | Deposit date: | 2021-04-26 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.513 Å) | | Cite: | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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7EP2
 | | Crystal structure of ZYG11B bound to GGFN degron | | Descriptor: | Protein zyg-11 homolog B | | Authors: | Yan, X, Li, Y. | | Deposit date: | 2021-04-26 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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7EP5
 | | Crystal structure of ZER1 bound to GKLH degron | | Descriptor: | Protein zer-1 homolog | | Authors: | Yan, X, Li, Y. | | Deposit date: | 2021-04-26 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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7EP1
 | | Crystal structure of ZYG11B bound to GFLH degron | | Descriptor: | Protein zyg-11 homolog B | | Authors: | Yan, X, Li, Y. | | Deposit date: | 2021-04-26 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.852 Å) | | Cite: | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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7EP4
 | | Crystal structure of ZER1 bound to GFLH degron | | Descriptor: | Protein zer-1 homolog | | Authors: | Yan, X, Li, Y. | | Deposit date: | 2021-04-26 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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5Y2D
 | | Crystal structure of H. pylori HtrA | | Descriptor: | Periplasmic serine endoprotease DegP-like, UNK-UNK-K-UNK-UNK-UNK-UNK-UNK-UNK-UNK, UNK-UNK-UNK, ... | | Authors: | Zhang, Z, Huang, Q, Tao, X. | | Deposit date: | 2017-07-25 | | Release date: | 2018-08-15 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.70009851 Å) | | Cite: | The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
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7E5Y
 | | Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD | | Descriptor: | 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1 | | Authors: | Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M. | | Deposit date: | 2021-02-21 | | Release date: | 2021-06-23 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.59 Å) | | Cite: | Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries.
Cell Discov, 7, 2021
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8CI0
 | | Maize Transketolase in complex with TPP and hydrolyzed (+)-Cornexistin | | Descriptor: | (1~{Z},3~{R},4~{S},7~{S},8~{Z})-8-ethylidene-4,7-bis(oxidanyl)-5-oxidanylidene-3-propyl-cyclononene-1,2-dicarboxylic acid, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, MAGNESIUM ION, ... | | Authors: | Freigang, J. | | Deposit date: | 2023-02-08 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.902 Å) | | Cite: | Investigations into Simplified Analogues of the Herbicidal Natural Product (+)-Cornexistin.
Chemistry, 29, 2023
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6PQ3
 | | Crystal structure of GDP-bound KRAS with ten residues long internal tandem duplication in the switch II region | | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Dharmaiah, S, Chan, A.H, Tran, T.H, Simanshu, D.K. | | Deposit date: | 2019-07-08 | | Release date: | 2020-05-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | RASinternal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling.
J.Biol.Chem., 295, 2020
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6WGH
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1KHO
 | | Crystal Structure Analysis of Clostridium perfringens alpha-Toxin Isolated from Avian Strain SWCP | | Descriptor: | ZINC ION, alpha-toxin | | Authors: | Justin, N, Moss, D.S, Titball, R.W, Basak, A.K. | | Deposit date: | 2001-11-30 | | Release date: | 2002-06-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
Biochemistry, 41, 2002
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