7XY6

Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM

Summary for 7XY6

Entry DOI	10.2210/pdb7xy6/pdb
EMDB information	33512
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
Functional Keywords	g protein coupled-receptor, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	145739.78
Authors	Zhang, J.Y.,Chen, Y.,Hua, T.,Song, G.J. (deposition date: 2022-05-31, release date: 2023-05-03, Last modification date: 2023-05-31)
Primary citation	Chen, Y.,Zhang, J.,Weng, Y.,Xu, Y.,Lu, W.,Liu, W.,Liu, M.,Hua, T.,Song, G. Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex. Sci Adv, 8:eadd3709-eadd3709, 2022 Cited by PubMed: 36563137 DOI: 10.1126/sciadv.add3709 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.99 Å)

Structure validation