7E5Y

Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD

Summary for 7E5Y

• Entry DOI: 10.2210/pdb7e5y/pdb
• Descriptor: Spike protein S1, 2B11 Fab Light chain, 2B11 Fab Heavy chain (3 entities in total)
• Functional Keywords: complex, antibody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 144038.74

Authors

Wu, H.,Yu, F.,Wang, Q.S.,Zhou, H.,Wang, W.W.,Zhao, T.,Pan, Y.B.,Yang, X.M. (deposition date: 2021-02-21, release date: 2021-06-23, Last modification date: 2023-11-29)

• Primary citation: Pan, Y.,Du, J.,Liu, J.,Wu, H.,Gui, F.,Zhang, N.,Deng, X.,Song, G.,Li, Y.,Lu, J.,Wu, X.,Zhan, S.,Jing, Z.,Wang, J.,Yang, Y.,Liu, J.,Chen, Y.,Chen, Q.,Zhang, H.,Hu, H.,Duan, K.,Wang, M.,Wang, Q.,Yang, X.; Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries.; Cell Discov, 7:57-57, 2021; PubMed: 34315862; DOI: 10.1038/s41421-021-00295-w

Experimental method

X-RAY DIFFRACTION (3.59 Å)