4GPU
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![BU of 4gpu by Molmil](/molmil-images/mine/4gpu) | |
4GVV
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![BU of 4gvv by Molmil](/molmil-images/mine/4gvv) | Crystal Structure of de novo design serine hydrolase OSH55.27, Northeast Structural Genomics Consortium (NESG) Target OR246 | Descriptor: | De novo design serine hydrolase | Authors: | Kuzin, A, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-08-31 | Release date: | 2012-09-12 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.895 Å) | Cite: | Northeast Structural Genomics Consortium Target OR246 To be Published
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2GH1
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![BU of 2gh1 by Molmil](/molmil-images/mine/2gh1) | Crystal Structure of the putative SAM-dependent methyltransferase BC2162 from Bacillus cereus, Northeast Structural Genomics Target BcR20. | Descriptor: | ACETATE ION, GLYCEROL, Methyltransferase | Authors: | Forouhar, F, Neely, H, Jayaraman, S, Ciao, M, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-03-24 | Release date: | 2006-04-04 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the putative SAM-dependent methyltransferase BC2162 from Bacillus cereus, Northeast Structural Genomics Target BcR20. To be Published
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2GF4
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![BU of 2gf4 by Molmil](/molmil-images/mine/2gf4) | Crystal structure of Vng1086c from Halobacterium salinarium (Halobacterium halobium). Northeast Structural Genomics Target HsR14 | Descriptor: | ACETATE ION, CALCIUM ION, Protein Vng1086c | Authors: | Benach, J, Zhou, W, Jayaraman, S, Forouhar, F.F, Janjua, H, Xiao, R, Ma, L.-C, Cunningham, K, Wang, D, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-03-21 | Release date: | 2006-04-18 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of Vng1086c from Halobacterium salinarium (Halobacterium halobium). Northeast Structural Genomics Target HsR14 To be Published
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2GAN
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![BU of 2gan by Molmil](/molmil-images/mine/2gan) | Crystal Structure of a Putative Acetyltransferase from Pyrococcus horikoshii, Northeast Structural Genomics Target JR32. | Descriptor: | 1,2-ETHANEDIOL, 182aa long hypothetical protein, SULFATE ION | Authors: | Forouhar, F, Abashidze, M, Jayaraman, S, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-03-09 | Release date: | 2006-03-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of a Putative Acetyltransferase from Pyrococcus horikoshii, Northeast Structural Genomics Target JR32. To be Published
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2G9D
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![BU of 2g9d by Molmil](/molmil-images/mine/2g9d) | Crystal Structure of Succinylglutamate desuccinylase from Vibrio cholerae, Northeast Structural Genomics Target VcR20 | Descriptor: | Succinylglutamate desuccinylase | Authors: | Zhou, W, Jayaraman, S, Forouhar, F, Conover, K, Rong, X, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-03-06 | Release date: | 2006-04-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Succinylglutamate desuccinylase from Vibrio cholerae, Northeast Structural Genomics Target VcR20. To be Published
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2GSV
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![BU of 2gsv by Molmil](/molmil-images/mine/2gsv) | X-Ray Crystal Structure of Protein YvfG from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR478. | Descriptor: | Hypothetical protein yvfG, SULFATE ION | Authors: | Forouhar, F, Su, M, Jayaraman, S, Wang, D, Fang, Y, Cunningham, K, Conover, K, Ma, L.-C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-04-26 | Release date: | 2006-05-09 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Hypothetical Protein YvfG from Bacillus subtilis, Northeast Structural Genomics Target SR478 To be Published
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2GVL
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![BU of 2gvl by Molmil](/molmil-images/mine/2gvl) | Crystal Structure of Murine NMPRTase | Descriptor: | Nicotinamide phosphoribosyltransferase | Authors: | Khan, J.A, Tao, X, Tong, L. | Deposit date: | 2006-05-02 | Release date: | 2006-07-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13, 2006
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2GZX
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![BU of 2gzx by Molmil](/molmil-images/mine/2gzx) | Crystal Structure of the TatD deoxyribonuclease MW0446 from Staphylococcus aureus. Northeast Structural Genomics Consortium Target ZR237. | Descriptor: | NICKEL (II) ION, putative TatD related DNase | Authors: | Vorobiev, S.M, Neely, H, Seetharaman, J, Wang, D, Fang, Y, Xiao, R, Acton, T, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-05-12 | Release date: | 2006-07-11 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the TatD deoxyribonuclease MW0446 from Staphylococcus aureus. Northeast Structural Genomics Consortium Target ZR237. To be Published
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2H3R
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![BU of 2h3r by Molmil](/molmil-images/mine/2h3r) | Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. | Descriptor: | Hypothetical protein BQLF2 | Authors: | Benach, J, Chen, Y, Seetharaman, J, Janjua, H, Xiao, R, Cunningham, K, Ma, L.-C, Ho, C.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-05-23 | Release date: | 2006-08-15 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of ORF52 from Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68). Northeast Structural Genomics Consortium target MhR28B. To be Published
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2H3W
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![BU of 2h3w by Molmil](/molmil-images/mine/2h3w) | Crystal structure of the S554A/M564G mutant of murine carnitine acetyltransferase in complex with hexanoylcarnitine and CoA | Descriptor: | (R)-3-CARBOXY-2-(HEXANOYLOXY)-N,N,N-TRIMETHYLPROPAN-1-AMINIUM, COENZYME A, carnitine acetyltransferase | Authors: | Hsiao, Y.S, Jogl, G, Tong, L. | Deposit date: | 2006-05-23 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates J.Biol.Chem., 281, 2006
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1GIC
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![BU of 1gic by Molmil](/molmil-images/mine/1gic) | CONCANAVALIN A COMPLEXED WITH METHYL ALPHA-D-GLUCOPYRANOSIDE | Descriptor: | CALCIUM ION, CONCANAVALIN A, MANGANESE (II) ION, ... | Authors: | Bradbrook, G.M, Gleichmann, T, Harrop, S.J, Helliwell, J.R, Habash, J, Kalb(Gilboa), A.J, Tong, L, Wan, T.C.M, Yariv, J. | Deposit date: | 1996-08-08 | Release date: | 1997-08-20 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure solution of a cubic crystal of concanavalin A complexed with methyl alpha-D-glucopyranoside. Acta Crystallogr.,Sect.D, 52, 1996
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2RJB
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![BU of 2rjb by Molmil](/molmil-images/mine/2rjb) | Crystal structure of uncharacterized protein YdcJ (SF1787) from Shigella flexneri which includes domain DUF1338. Northeast Structural Genomics Consortium target SfR276 | Descriptor: | Uncharacterized protein, ZINC ION | Authors: | Seetharaman, J, Chen, Y, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-10-14 | Release date: | 2007-10-30 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of uncharacterized protein YdcJ (SF1787) from Shigella flexneri which includes domain DUF1338. To be Published
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6DDY
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![BU of 6ddy by Molmil](/molmil-images/mine/6ddy) | Crystal structure of the double mutant (D52N/K359Q) of NT5C2-537X in the active state, Northeast Structural Genomics Target | Descriptor: | Cytosolic purine 5'-nucleotidase, GLYCEROL, PHOSPHATE ION | Authors: | Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2018-05-10 | Release date: | 2018-07-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell, 34, 2018
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6DDX
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![BU of 6ddx by Molmil](/molmil-images/mine/6ddx) | Crystal structure of the double mutant (D52N/L375F) of NT5C2-537X in the active state, Northeast Structural Genomics Target | Descriptor: | Cytosolic purine 5'-nucleotidase, PHOSPHATE ION | Authors: | Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2018-05-10 | Release date: | 2018-07-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.901 Å) | Cite: | Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell, 34, 2018
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6E12
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![BU of 6e12 by Molmil](/molmil-images/mine/6e12) | Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141 | Descriptor: | Alr8543 protein, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Forouhar, F, Neely, H, Seetharaman, J, Xiao, R, Ciccosanti, C, Patel, D, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2018-07-09 | Release date: | 2018-07-25 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141 To Be Published
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6E35
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![BU of 6e35 by Molmil](/molmil-images/mine/6e35) | Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160 | Descriptor: | 2-(1H-indol-3-yl)ethanol, CYANIDE ION, Indoleamine 2,3-dioxygenase 1, ... | Authors: | Forouhar, F, Lewis-Ballester, A, Lew, S, Karkashon, S, Seetharaman, J, Lu, C, Hussain, M, Yeh, S.-R, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2018-07-13 | Release date: | 2018-07-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.411 Å) | Cite: | Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160 To Be Published
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3LM8
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![BU of 3lm8 by Molmil](/molmil-images/mine/3lm8) | Crystal Structure of Thiamine pyrophosphokinase from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR677 | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Kuzin, A, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-29 | Release date: | 2010-03-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Northeast Structural Genomics Consortium Target SR677 To be Published
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3LZ7
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![BU of 3lz7 by Molmil](/molmil-images/mine/3lz7) | Crystal Structure of thioesterase HI1161 EC3.1.2.- from Haemophilus influenzae. Orthorombic crystal form. Northeast Structural Genomics Consortium Target IR63 | Descriptor: | DI(HYDROXYETHYL)ETHER, Putative esterase HI1161 | Authors: | Kuzin, A, Min, S, Seetharaman, J, Janjua, J, Xiao, R, Foote, E.L, Ciccosanti, C, Cooper, B, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-03-01 | Release date: | 2010-03-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.191 Å) | Cite: | Northeast Structural Genomics Consortium Target IR63 To be Published
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3LMF
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![BU of 3lmf by Molmil](/molmil-images/mine/3lmf) | Crystal Structure of Nmul_A1745 protein from Nitrosospira multiformis, Northeast Structural Genomics Consortium Target NmR72 | Descriptor: | Uncharacterized protein | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-29 | Release date: | 2010-02-16 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Northeast Structural Genomics Consortium Target NmR72 To be Published
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3LMM
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![BU of 3lmm by Molmil](/molmil-images/mine/3lmm) | Crystal Structure of the DIP2311 protein from Corynebacterium diphtheriae, Northeast Structural Genomics Consortium Target CdR35 | Descriptor: | CHLORIDE ION, COBALT (II) ION, Uncharacterized protein | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Buchwald, W.A, Maglaqui, M, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-31 | Release date: | 2010-02-16 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Northeast Structural Genomics Consortium Target CdR35 To be Published
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3LV4
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![BU of 3lv4 by Molmil](/molmil-images/mine/3lv4) | Crystal structure of the glycoside hydrolase, family 43 YxiA protein from Bacillus licheniformis. Northeast Structural Genomics Consortium Target BiR14. | Descriptor: | ACETATE ION, CALCIUM ION, Glycoside hydrolase YxiA | Authors: | Vorobiev, S, Abashidze, M, Seetharaman, J, Belote, R.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-02-19 | Release date: | 2010-03-09 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.695 Å) | Cite: | Crystal structure of the glycoside hydrolase, family 43 YxiA protein from Bacillus licheniformis. To be Published
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3LYU
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![BU of 3lyu by Molmil](/molmil-images/mine/3lyu) | Crystal Structure of the C-terminal domain (residues 83-215) of PF1911 hydrogenase from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR246A | Descriptor: | Putative hydrogenase | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Foote, E.L, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-02-28 | Release date: | 2010-03-23 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Northeast Structural Genomics Consortium Target PfR246A To be Published
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3LYS
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![BU of 3lys by Molmil](/molmil-images/mine/3lys) | Crystal Structure of the N-terminal domain of the Prophage pi2 protein 01 (integrase) from Lactococcus lactis, Northeast Structural Genomics Consortium Target KR124F | Descriptor: | Prophage pi2 protein 01, integrase | Authors: | Forouhar, F, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-02-28 | Release date: | 2010-03-16 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Northeast Structural Genomics Consortium Target KR124F To be Published
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3MPR
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![BU of 3mpr by Molmil](/molmil-images/mine/3mpr) | Crystal Structure of endonuclease/exonuclease/phosphatase family protein from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR318A | Descriptor: | ACETIC ACID, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kuzin, A, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-04-27 | Release date: | 2010-05-26 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Northeast Structural Genomics Consortium Target BtR318A To be Published
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