6E42

CRYSTAL STRUCTURE OF HUMAN INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) in complex with ferric heme and 4-Chlorophenyl imidazole

Summary for 6E42

Entry DOI	10.2210/pdb6e42/pdb
Descriptor	Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-(3-chlorophenyl)-1H-imidazole, ... (5 entities in total)
Functional Keywords	ido1, 4-chlorophenyl imidazole, inhibitor complex, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	186622.40
Authors	Luo, S.,Tong, L. (deposition date: 2018-07-16, release date: 2018-11-14, Last modification date: 2024-03-13)
Primary citation	Luo, S.,Xu, K.,Xiang, S.,Chen, J.,Chen, C.,Guo, C.,Tong, Y.,Tong, L. High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form. Acta Crystallogr F Struct Biol Commun, 74:717-724, 2018 Cited by PubMed: 30387777 DOI: 10.1107/S2053230X18012955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.103 Å)

Structure validation